Table 1 Basic characteristics of study subjects by groups.

From: C-reactive protein to platelet ratio as an early biomarker in differentiating neonatal late-onset sepsis in neonates with pneumonia

Variables

Pneumonia (n = 1211)

Sepsis (n = 174)

P

Age (days)

12.0 (7.0, 20.0)

12.0 (8.0, 16.0)

0.632

Gestational age (weeks)

39.3 ± 1.2

38.1 ± 1.0

< 0.001

Male, n (%)

717 (59.2%)

100 (57.5%)

0.663

Weight (kg)

3.3 ± 0.6

2.9 ± 0.9

< 0.001

Temperature (℃)

37.0 ± 0.5

37.1 ± 0.9

0.108

Respiratory (rate/min)

51.0 ± 10.6

51.6 ± 12.1

0.537

Respiratory rate > 60 rate/min, n (%)

206 (17.0%)

37 (21.3%)

0.168

Heart rate (bpm)

148.0 ± 16.0

150.9 ± 21.6

0.085

SBP (mm Hg)

77.1 ± 8.0

74.7 ± 10.9

0.005

DBP (mm Hg)

46.9 ± 7.8

44.5 ± 9.4

0.001

Biochemical parameters

 PCT (ng/ml)

0.11 (0.08, 0.16)

0.46 (0.14, 7.36)

< 0.001

 CRP (mg/L)

0.7 (0.7, 0.7)

0.7 (0.7, 28.1)

< 0.001

 ALT (U/L)

27.9 (21.3, 36.7)

25.2 (19.2, 38.0)

0.207

 AST (U/L)

35.0 (27.6, 44.9)

34.8 (27.8, 48.2)

0.527

 CREA

41.6 (32.3, 51.4)

47.1 (36.4, 73.1)

< 0.001

 UREA

2.5 (1.6, 3.6)

3.7 (2.6, 5.4)

< 0.001

 WBC (106 cells/L)

9.7 (7.8, 11.9)

10.6 (7.5, 14.9)

0.016

 Neutrophils (106 cells/L)

3.8 (2.7, 5.4)

5.7 (3.3, 9.1)

< 0.001

 Lymphocytes (106 cells/L)

4.3 (3.3, 5.5)

3.2 (1.9, 4.7)

< 0.001

 PLT (109 cells/L)

330.1 (254.0, 410.0)

234.5 (98.0, 360.7)

< 0.001

CPR (mg/108 cells)

0.02 (0.02, 0.03)

0.07 (0.02, 2.01)

< 0.001

Mechanical ventilation, n (%)

304 (25.1%)

61 (35.1%)

0.005

Length of hospital stay (days)

9.0 (8.0, 12.0)

17.0 (13.0, 26.0)

< 0.001

  1. Significant values are in bold.
  2. SBP systolic blood pressure, DBP diastolic blood pressure, PCT procalcitonin, CRP C-reactive protein, ALT alanine aminotransferase, AST aspartate aminotransferase, CREA creatinine, UREA urea nitrogen, WBC White blood cells, PLT Platelet, CPR C-reactive protein to platelet ratio.
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