Fig. 2
From: Cortical thickness deviations as biomarker for subtyping and prognosis in pediatric brainstem tumors
Heterogeneity analysis of cerebral CTh in patients with brainstem tumors. (a) Schematic diagram illustrating the curve fitting process for the Gaussian Process Regression (GPR) normative model. Line graphs display the cortical thickness (CTh) trajectory with age. Blue line represents the modeled trend. Brain maps below represent one patient’ spatial overlap maps of deviations. Color scale indicates z-score with warm colors for positive deviations and cool colors for negative deviations. (b) Butterfly diagram depicting the extreme deviation rate across different brain regions. X-axis refers to number of extremely deviated regions. Y-axis refers to percentage of cases, showing the distribution of extreme deviation counts across groups. (c) Spatial overlap map showing areas of positive deviation and negative deviation of CTh in patients and healthy children (HCs). (d) Comparative analysis highlighting differences in CTh deviations between patients and healthy children. The red areas refers to significant brain regions.
