Table 2 Clinical characteristic differences between subtypes.

From: Cortical thickness deviations as biomarker for subtyping and prognosis in pediatric brainstem tumors

Variable

Category

Subtype 1

Subtype 2

p

N (%)

Median (IQR, range)

N (%)

Median (IQR, range)

Age/years

–

–

8 (5–11, 14)

 

9 (7–11, 12)

0.034

Gender

Boy

51 (51%)

–

21 (47%)

–

0.762

Girl

49 (49%)

–

24 (53%)

–

 

Headache

Positive

28 (28%)

–

13 (29%)

–

1.000

Negative

72 (72%)

–

32 (71%)

–

 

Nausea

Positive

28 (28%)

–

14 (31%)

–

0.854

Negative

72 (72%)

–

31 (89%)

–

 

Diplopia

Positive

46 (46%)

–

21 (47%)

–

1.000

Negative

54 (54%)

–

24 (53%)

–

 

Bucking

Positive

41 (41%)

–

22 (49%)

–

0.340

Negative

59 (59%)

–

23 (51%)

–

 

Dysphagia

Positive

17 (17%)

–

6 (13%)

–

0.754

Negative

83 (83%)

–

39 (87%)

–

 

Dysarthria

Positive

25 (25%)

–

11 (24%)

–

1.000

Negative

75 (75%)

–

34 (76%)

–

 

Weakness

Positive

43 (43%)

–

18 (40%)

–

0.875

Negative

57 (57%)

–

27 (60%)

–

 

Ataxia

Positive

46 (46%)

–

19 (42%)

–

0.808

Negative

54 (54%)

–

26 (58%)

–

 

Tumor growth pattern

Focal

18 (18%)

–

13 (29%)

 

0.207

Diffuse

82 (82%)

–

32 (71%)

  

Duration/months

–

–

2.0 (1.0–3.0, 59.8)

–

2.0 (1.0–3.0, 70.8)

0.247

KPS/scores

–

–

80 (70–80, 60)

–

80 (70–80, 50)

0.801

Tumor volume/mm3

–

–

25.9 (17.7–34.4, 68.5)

–

25.5 (14.3–34.4, 67.9)

0.517

  1. IQR interquartile range, KPS Karnofsky performance status.