Table 3 Univariate and multivariate analyses of the cohort of HSCT recipients (binary logistic regression using mortality as the response variable).

From: Nationwide study of COVID-19 outcomes in hematologic patients following bone marrow transplantation

 

Univariate

Multivariate

OR1

95% CI1

p value

OR1

95% CI1

p value

Age

1.01

1.00, 1.02

0.007

1.02

1.02, 1.03

< 0.001

Sex (men)

0.97

0.75, 1.24

0.8

1.09

0.81, 1.45

0.6

ICU admissions

0.10

0.07, 0.12

< 0.001

0.13

0.09, 0.19

< 0.001

ICU LOS

1.08

1.07, 1.10

< 0.001

1.01

1.00, 1.03

0.079

Hospitalization LOS

1.03

1.02, 1.03

< 0.001

1.01

1.01, 1.02

< 0.001

Comorbidities

Type 2 diabetes

0.86

0.58, 1.26

0.5

0.67

0.42, 1.05

0.093

Coronary disease

0.96

0.44, 1.84

0.9

0.60

0.25, 1.29

0.2

Heart failure

2.58

1.63, 3.97

< 0.001

1.42

0.81, 2.44

0.2

Hypertension

1.12

0.84, 1.47

0.4

1.22

0.87, 1.70

0.2

Cerebrovascular disease

6.73

0.81, 56.3

0.074

5.54

0.38, 90.5

0.2

Obesity

0.58

0.26, 1.13

0.11

0.51

0.21, 1.09

0.11

Dementia

6.77

1.59, 28.8

0.012

8.89

1.79, 41.9

0.005

Chronic kidney disease

1.15

0.74, 1.73

0.5

1.30

0.78, 2.12

0.3

Chronic liver disease

0.67

0.04, 3.51

0.7

0.30

0.02, 1.80

0.3

Chronic pulmonary disease

0.83

0.50, 1.30

0.4

1.06

0.61, 1.76

0.8

Solid tumor

2.35

1.46, 3.68

< 0.001

3.63

2.09, 6.14

< 0.001

Hematologic malignancies

Hodgkin lymphoma

0.79

0.33, 1.63

0.5

1.37

0.51, 3.18

0.5

Non-Hodgkin lymphoma

1.02

0.74, 1.39

0.9

1.10

0.72, 1.65

0.7

Multiple myeloma and malignant plasma cell neoplasms

0.74

0.54, 1.01

0.054

0.93

0.61, 1.40

0.7

Acute leukemia

1.43

1.10, 1.85

0.008

1.72

1.21, 2.46

0.003

Chronic myeloproliferative disorders

2.02

1.08, 3.55

0.028

0.96

0.45, 1.93

> 0.9

  1. 1OR = odds ratio, CI = confidence interval. LOS: length of stay, in days.