Table 3 Univariate and multivariate analyses of the cohort of HSCT recipients (binary logistic regression using mortality as the response variable).
From: Nationwide study of COVID-19 outcomes in hematologic patients following bone marrow transplantation
Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
OR1 | 95% CI1 | p value | OR1 | 95% CI1 | p value | |
Age | 1.01 | 1.00, 1.02 | 0.007 | 1.02 | 1.02, 1.03 | < 0.001 |
Sex (men) | 0.97 | 0.75, 1.24 | 0.8 | 1.09 | 0.81, 1.45 | 0.6 |
ICU admissions | 0.10 | 0.07, 0.12 | < 0.001 | 0.13 | 0.09, 0.19 | < 0.001 |
ICU LOS | 1.08 | 1.07, 1.10 | < 0.001 | 1.01 | 1.00, 1.03 | 0.079 |
Hospitalization LOS | 1.03 | 1.02, 1.03 | < 0.001 | 1.01 | 1.01, 1.02 | < 0.001 |
Comorbidities | ||||||
Type 2 diabetes | 0.86 | 0.58, 1.26 | 0.5 | 0.67 | 0.42, 1.05 | 0.093 |
Coronary disease | 0.96 | 0.44, 1.84 | 0.9 | 0.60 | 0.25, 1.29 | 0.2 |
Heart failure | 2.58 | 1.63, 3.97 | < 0.001 | 1.42 | 0.81, 2.44 | 0.2 |
Hypertension | 1.12 | 0.84, 1.47 | 0.4 | 1.22 | 0.87, 1.70 | 0.2 |
Cerebrovascular disease | 6.73 | 0.81, 56.3 | 0.074 | 5.54 | 0.38, 90.5 | 0.2 |
Obesity | 0.58 | 0.26, 1.13 | 0.11 | 0.51 | 0.21, 1.09 | 0.11 |
Dementia | 6.77 | 1.59, 28.8 | 0.012 | 8.89 | 1.79, 41.9 | 0.005 |
Chronic kidney disease | 1.15 | 0.74, 1.73 | 0.5 | 1.30 | 0.78, 2.12 | 0.3 |
Chronic liver disease | 0.67 | 0.04, 3.51 | 0.7 | 0.30 | 0.02, 1.80 | 0.3 |
Chronic pulmonary disease | 0.83 | 0.50, 1.30 | 0.4 | 1.06 | 0.61, 1.76 | 0.8 |
Solid tumor | 2.35 | 1.46, 3.68 | < 0.001 | 3.63 | 2.09, 6.14 | < 0.001 |
Hematologic malignancies | ||||||
Hodgkin lymphoma | 0.79 | 0.33, 1.63 | 0.5 | 1.37 | 0.51, 3.18 | 0.5 |
Non-Hodgkin lymphoma | 1.02 | 0.74, 1.39 | 0.9 | 1.10 | 0.72, 1.65 | 0.7 |
Multiple myeloma and malignant plasma cell neoplasms | 0.74 | 0.54, 1.01 | 0.054 | 0.93 | 0.61, 1.40 | 0.7 |
Acute leukemia | 1.43 | 1.10, 1.85 | 0.008 | 1.72 | 1.21, 2.46 | 0.003 |
Chronic myeloproliferative disorders | 2.02 | 1.08, 3.55 | 0.028 | 0.96 | 0.45, 1.93 | > 0.9 |