Fig. 10

Immune cell infiltration and TME studies. (A–C) Differences in tumor-infiltrating immune cells, immune-related functions and tumor-infiltrating lymphocytes between AML patients in the high- and low-risk groups. The interquartile range of values was represented by the upper and lower ends of the boxes. The median values are represented by the median lines of the boxes, and the outliers are represented by the black dots. The statistical P-value is represented by the asterisks (*P < 0.05). (D) Differences in immune checkpoint expression between the high-risk and low-risk groups. The statistical differences were tested by the one-way ANOVA between the high- risk and low-risk groups. The statistical P-value was represented by the asterisks (*P < 0.05). (E, F) Comparison of ESTIMATE score and tumor purity in the high- and low- risk group. The statistical differences were tested by the one-way ANOVA between the high- risk and low-risk groups. The statistical P-value was represented by the asterisks (*P < 0.05; ***P < 0.001).