Table2 Univariate analysis identifying prognostic factors for OS and DSS.
From: Neck dissection improves the prognosis of patients with early-stage oral squamous cell carcinoma
Variables | Diseases-specific survival | Overall survival | ||
|---|---|---|---|---|
HR(95%CI) | P-value | HR(95%CI) | P-value | |
Age | ||||
< 65 years | Ref | Ref | ||
≥ 65 years | 1.47 (1.36,1.59) | < 0.001 | 2.17 (2.05,2.3) | < 0.001 |
Sex | ||||
Male | Ref | Ref | ||
Female | 1.17 (1.08,1.27) | < 0.001 | 1.04 (0.98,1.1) | 0.158 |
Site | ||||
Lip | Ref | Ref | ||
Tongue | 4.01 (3.35,4.79) | < 0.001 | 1.08 (1,1.17) | 0.046 |
Gum | 5.18 (4.17,6.44) | < 0.001 | 1.55 (1.38,1.74) | < 0.001 |
Floor of mouth | 4.79 (3.89,5.9) | < 0.001 | 1.59 (1.43,1.77) | < 0.001 |
Palate | 6.09 (4.83,7.68) | < 0.001 | 1.84 (1.62,2.1) | < 0.001 |
Buccal mucosa | 5.97 (4.85,7.36) | < 0.001 | 1.72 (1.54,1.93) | < 0.001 |
Others | 6.37 (4.58,8.84) | < 0.001 | 1.64 (1.31,2.07) | < 0.001 |
Marital status | ||||
Married | Ref | Ref | ||
Others | 1.45 (1.34,1.57) | < 0.001 | 1.56 (1.48,1.65) | < 0.001 |
Race | ||||
White | Ref | Ref | ||
Black | 1.68 (1.41,1.99) | < 0.001 | 1.44 (1.26,1.63) | < 0.001 |
Others | 1.04 (0.9,1.21) | 0.564 | 0.78 (0.69,0.87) | < 0.001 |
Residence | ||||
Urban | Ref | Ref | ||
Rural | 0.93 (0.83,1.04) | 0.217 | 1.1 (1.02,1.19) | 0.009 |
Income | ||||
< 50,000 | Ref | Ref | ||
50,000–75,000 | 0.94 (0.81,1.09) | 0.399 | 0.93 (0.84,1.03) | 0.145 |
> 75,000 | 0.82 (0.71,0.95) | 0.007 | 0.81 (0.73,0.89) | < 0.001 |
Grade | ||||
I | Ref | Ref | ||
II | 1.9 (1.72,2.11) | < 0.001 | 1.38 (1.29,1.47) | < 0.001 |
III | 2.67 (2.37,3.01) | < 0.001 | 1.61 (1.48,1.75) | < 0.001 |
Neck dissection | ||||
No | Ref | |||
Yes | 0.86 (0.79,0.94) | < 0.001 | 0.75(0.7–0.8) | < 0.001 |
Radiation | ||||
No | Ref | |||
Yes | 2.33 (2.15,2.52) | < 0.001 | 1.51 (1.42,1.6) | < 0.001 |
Chemotherapy | ||||
No | Ref | |||
Yes | 1.93 (1.75,2.14) | < 0.001 | 1.26 (1.16,1.37) | < 0.001 |
