Fig. 4

Drug sensitivity analysis of 7 related genes. (A) The gene set drug sensitivity analysis from Genomics of Drug Sensitivity in Cancer (GDSC) IC50 drug data. (B) The gene set drug sensitivity analysis from Cancer Therapeutics Response Portal (CTRP) IC50 drug data. The Pearson’s correlation indicates the correlation between gene expression and drug sensitivity. Blue bubbles represent negative correlations, and red bubbles represent positive correlations; the deeper the color, the higher the correlation. The bubble size was positively correlated with the FDR significance. The black outline indicates an FDR < 0.05. Only the top 30 ranked drugs were included.