Table 3 Summary of the different regions of chromosomal aberration between non-response and response group.

From: Identifying a unique chromosomal pattern to predict the gemcitabine response in patients with cholangiocarcinoma

Chromosome

Region

R(H)/S(L)

R(L)/S(H)

Accession

Start

Stop

Gene symbol

NCBI gene ID

Name

2

2q37.2

 √

 

NC_000002.12

234,682,668

234,717,764

LINC01173

106,144,537

Long intergenic non-protein coding RNA 1173

4

4q32.1

 

 √

Noncoding gene

5

5q12.3

 

 √

NC_000005.10

64,768,918

65,018,763

CWC27

10,283

CWC27 spliceosome associated cyclophilin

10

10q21.3

 

 √

NC_000010.10

67,672,281

69,455,953

CTNNA3

29,119

Catenin alpha 3

 

10q31.32

 √

 

Noncoding gene

11

11p11.2

 

 √

Noncoding gene

 

11q13.3

 √

 

Noncoding gene

 

11q14.2

 

 √

NC_000011.10

86,672,237

86,753,297

ME3-DT

107,984,427

 
 

11q14.1(2)

 √

 

NC_000011.10

78,652,829

79,441,030

TENM4

26,011

Teneurin transmembrane protein 4

16

16p11.2

 

 √

NC_000011.9

31,453,948

31,531,169

IMMP1L

196,294

Inner mitochondrial membrane peptidase subunit 1

 

16q22.3

 √

 

NC_000011.9

73,386,683

73,472,119

RAB6A

5870

RAB6A, member RAS oncogene family

 

16q23.3

 √

 

NC_000016.10

82,626,823

83,800,640

CDH13

1012

Cadherin 13

17

17q22

 

 √

NC_000017.10

57,785,015

57,919,616

VMP1

81,671

Cacuole membrane protein 1

21

21q21.3

 

 √

Noncoding gene

22

22q12.3

 

 √

NC_000022.10

36,956,904

37,099,797

CACNG2

10,369

Calcium voltage-gated channel auxiliary subunit gamma 2

  1. Chromosomal aberrations were analyzed by MetaboAnalyst program with Log 2 Ratio. A high Log 2 Ratio in was demonstrated in the non-response group, but low in the response group in the following locations: chromosome 2 (2q37.2), 10 (10q31.32), 11 (11q13.3, 11q14.1) and 16 (16q22.3, 16q23.3), Log 2 Ratio in the non-response group was low, but high in the response group in the following locations: chromosome 4 (4q32.1), 5 (5q12.3), 10 (10q21.3), 11 (11p11.2, 11q14.2), 16 (16p11.2), 17q (17q22), 21 (21q21.3) and 22 (22q12.3).