Table 3 Epidemiology of causative pathogens of the studied population with infective endocarditis across three distinct periods.
From: Trends in infective endocarditis over two decades in a Thai tertiary care setting
Total (N = 435) | 1998–2001 (N = 134) | 2012–2015 (N = 117) | 2016–2020 (N = 184) | p-value | |
|---|---|---|---|---|---|
Streptococci | 195 (44.8%) | 55 (41.0%) | 58 (49.6%) | 82 (44.6%) | 1.000 |
Staphylococci | 76 (17.5%) | 22 (16.4%) | 14 (12.0%) | 40 (21.7%) | 0.504 |
Enterococci | 23 (5.3%) | 5 (3.7%) | 5 (4.3%) | 13 (7.1%) | 0.528 |
Others | 18 (4.1%) | 5 (3.7%) | 8 (6.8%) | 5 (2.7%) | 1.000 |
Culture negative | 131 (30.1%) | 51 (38.1%) | 36 (30.8%) | 44 (23.9%) | 0.018 |
Identification of the pathogens | |||||
Viridans group streptococci | 72 (16.6%) | 33 (24.6%) | 10 (8.5%) | 29 (15.8%) | 0.051 |
Unidentified alpha-hemolytic streptococci | 27 (6.2%) | 4 (3.0%) | 10 (8.5%) | 13 (7.1%) | 1.000 |
Streptococcus suis | 38 (8.7%) | 6 (4.5%) | 8 (6.8%) | 24 (13.0%) | 0.042 |
Streptococcus bovis | 24 (5.5%) | 0 (0.0%) | 15 (12.8%) | 9 (4.9%) | < 0.001 |
Streptococcus agalactiae | 21 (4.8%) | 0 (0.0%) | 7 (6.0%) | 14 (7.6%) | 0.012 |
Streptococcus pneumoniae | 3 (0.7%) | 2 (1.5%) | 0 (0.0%) | 1 (0.5%) | 0.924 |
Staphylococcus aureus | 56 (12.9%) | 17 (12.7%) | 11 (9.4%) | 28 (15.2%) | 1.000 |
Staphylococcus epidermidis | 4 (0.9%) | 0 (0.0%) | 1 (0.9%) | 3 (1.6%) | 0.462 |
Other coagulase-negative staphylococci | 8 (1.8%) | 1 (0.7%) | 1 (0.9%) | 6 (3.3%) | 0.330 |
Enterococcus faecalis | 20 (4.6%) | 4 (3.0%) | 3 (2.6%) | 13 (7.1%) | 0.327 |
Enterococcus faecium | 1 (0.2%) | 0 (0.0%) | 1 (0.9%) | 0 (0.0%) | 1.000 |
HACEK | 2 (0.5%) | 0 (0.0%) | 1 (0.9%) | 1 (0.5%) | 1.000 |
