Fig. 2 | Scientific Reports

Fig. 2

From: Accelerated vaccine process development by orthogonal protein characterization

Fig. 2

Direct implementation of RP-HPLC method to monitor progressive increase in antigen purity during downstream purification. UV215nm chromatograms corresponding to (A) crude fermenter supernatant, (B) post-CaptoMMC chromatography, (C) post-Hypercel chromatography and (D) purified drug substance for ancestral spike antigen production. Asterisk (*) denotes peak containing spike protein antigen.

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