Fig. 3

Copy-number plots of tumors and matched prior adenomas from two recurrent patients, where the y-axis represents copy number (normalized log2 ratio) and the x-axis represents chromosomes. (A) Sample of case 1 with first adenoma resection. (B) Sample of case 1 with progression-to-adenocarcinoma resection. (C) Sample of case 2 with first adenoma resection. (D) Sample of case 2 with progression-to-adenocarcinoma resection.