Fig. 2

Heterogeneous signaling pathways and drug responses between the two lactylation activity phenotypes. (A) Bar graph showing the differential GSVA scores in KEGG pathways between the low- and high-lactylation activity phenotypes. (B) Heatmap of the GSVA score in KEGG pathways with p ≤ 0.1 and |t| ≥ 2 across blood samples. (C) Box plot showing the differential IC50 values of drugs between the two phenotypes. The KEGG images were constructed as per the citation guidelines: www.kegg.jp/kegg/kegg1.html.