Table 1 The clincal characteristics of critically ill patients with sepsis-associated ARDS between the two lactylation activity phenotypes.

From: Characterization of lactylation-based phenotypes and molecular biomarkers in sepsis-associated acute respiratory distress syndrome

Characteristics

Total

(n = 31)

High-lactylation (n = 18)

Low-lactylation (n = 13)

p-value

Age, mean (SD)

53.4 (14.0)

57.2 (15.1)

48.6 (10.3)

0.074

Gender, n (%)

> 0.999

 Male

15 (48.39)

9 (50.0)

6 (46.15)

 

 Female

16 (51.61)

9 (50.0)

7 (53.85)

 

Ethnicity, n (%)

0.880

 White

27 (87.1)

16 (88.9)

11(84.6)

 

 Black

0 (0.0)

0 (0.0)

0 (0.0)

 

 Asian

1 (3.2)

0 (0.0)

1 (7.7)

 

 Others

3 (9.7)

2 (11.1)

1 (7.7)

 

APACHE II, mean (SD)

37.7 (13.7)

42.6 (14.1)

31.0 (10.0)

0.017

Hospital stay, median (IQR)

17.0 (10.0–43.0)

36.0 (11.0-49.5)

11.0 (8.0–20.0)

0.028

Mortality, n (%)

 Hospital

10 (32.3)

8 (44.4)

2 (15.4)

0.129

 28-day

13 (41.9)

10 (55.6)

2 (15.4)

0.032

 One-year

15 (48.4)

12 (66.7)

3 (23.1)

0.029

  1. APACHE II, the Acute Physiology and Chronic Health Evaluation II; ARDS, acute respiratory distress syndrome; IQR, internal quartile range; SD, standard deviation.