Table 2 Association between carotid properties, TRFs, and IS.

From: Association of carotid atherosclerosis, perivascular adipose tissue, and stiffness by ultrasound assessment in young adults with ischemic stroke

 

Univariate

Multivariate

OR

95% CI

P-valuea

OR

95% CI

P-value

Risk factors

  Age at examination

0.995

0.961–1.030

0.777

   

 Sex

1.000

0.634–1.578

1.000

   

 BMI

4.681

3.339–6.564

< 0.0001

2.764

1.697–4.503

< 0.0001b

 SBP

1.202

1.160–1.246

< 0.0001

1.131

1.074–1.192

< 0.0001b

 DBP

1.267

1.208–1.329

< 0.0001

1.148

1.062–1.241

< 0.0001b

 Diabetes mellitus

3.101

1.779–5.408

< 0.0001

2.036

0.606–6.839

0.250b

 Current smoker

2.296

1.515–3.482

< 0.0001

1.737

0.854–3.531

0.127b

Biochemical index

 TC

7.808

5.085–11.991

< 0.0001

3.446

1.755–6.767

< 0.0001b

 TG

2.262

1.645–3.109

< 0.0001

1.162

0.638–2.118

0.624b

 LDL

5.292

3.713–7.543

< 0.0001

2.416

1.324–4.408

0.004b

 HDL

0.161

0.033–0.781

0.023

0.022

0.001–0.359

0.007b

Carotid measurements

 The presence of plaque

5.333

3.443–8.261

< 0.0001

1.448

0.721–2.909

0.298c

 IMT

1.506

1.310–1.732

< 0.0001

0.996

0.769–1.291

0.977c

 EMT

2.755

2.257–3.364

< 0.0001

2.118

1.612–2.782

< 0.0001c

 FAI

1.253

1.200–1.307

< 0.0001

1.070

1.005–1.138

0.033c

  1. Values in bold indicate a P-value of less than 0.05.
  2. OR, odds ratio; CI, confidence interval; IS, ischemic stroke; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triglycerides; LDL, low density lipoprotein; HDL, high density lipoprotein; EMT, extra-media thickness; IMT, intima-media thickness; FAI, flow augmentation index; TRF, traditional risk factor.
  3. aThe univariate logistic regression models were constructed to assess the association between all the TRFs and IS in young adults.
  4. bThe multivariate logistic regression models were constructed to assess the association between TRFs associated with IS and IS in young adults.
  5. cThe multivariate logistic regression models (adjusted for BMI, SBP, DBP, TC, LDL, and HDL) were constructed to assess the association between all the carotid measurements obtained by ultrasound and IS in young adults.
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