Fig. 3
From: Staphylococcus saprophyticus prevents skin damage by inhibiting Staphylococcus aureus quorum sensing
S. saprophyticus culture supernatant inhibits Agr type-I and -II signaling in S. aureus. (a–l) S. aureus LAC (Agr type-I), HFH-30008 (Agr type-II), MW2 (Agr type-III), and HFH-30032 (Agr type-IV) strains were grown in 30% filtered spent media from S. saprophyticus and S. auricularis for 8 h. Growth (a, d, g, j) in TSB at 8 h and the expression of psmα (b, e, h, k) and RNAIII (c, f, i, l) after 8 h of growth as measured by qRT-PCR are shown. psmα and RNAIII expression levels are relative to that of the S. aureus housekeeping gene, gyrB. Data are mean ± SD from three independent experiments. n.s., not significant, *p < 0.05, **p < 0.01 versus TSB (–) according to one-way ANOVA with Tukey’s correction.
