Fig. 8 | Scientific Reports

Fig. 8

From: Staphylococcus saprophyticus prevents skin damage by inhibiting Staphylococcus aureus quorum sensing

Fig. 8

S. saprophyticus AIP protects skin damage by intradermal inoculation with S. aureus. (a–c) Representative macroscopic and hematoxylin and eosin-stained microscopic images (a), skin lesion sizes at the indicated time points (b), and S. aureus CFU in the skin (c) of mice intradermally inoculated with S. aureus LAC WT strain containing DMSO (–) or S. saprophyticus AIP (250 μg) at 6 days post-infection (n = 5). Findings for mice colonized with S. aureus LAC Δagr are shown for comparison. In c, each dot represents a mouse. Data are representative of three independent experiments. n.s., not significant, ****p < 0.0001 according to one-way ANOVA with Tukey’s correction.

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