Fig. 7 | Scientific Reports

Fig. 7

From: Regulatory mechanism and prognostic value of sex hormone pathways connected with metabolism and immune signaling in clear cell renal cell carcinoma

Fig. 7

Genetic alterations and their implications in low and high-SHAG score ccRCC patients. (A) Tumoral mutation burden comparison between low- and high-SHAG score patients. (B) Representation of the extent of copy number alterations in low- and high-SHAG score. (C) Mutation frequency of specific genes including PBRM1, SETD2, BAP1, MUC16, and KDM5 C. (D) Volcano plot highlighting differentially expressed genes between patients with genomic alterations and those without. (E) SCGN gene expression distribution between patients with and without genomic alterations. (F) Kaplan-Meier survival curve elucidating the relationship between SCGN expression levels and overall survival.

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