Table 2 COX RFS positive.
From: Comprehensive analysis of UPK3B as a marker for prognosis and immunity in pancreatic adenocarcinoma
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Pathologic T stage | 177 | 0.002 | |||
T1&T2 | 31 | Reference | Reference | ||
T3&T4 | 146 | 2.425 (1.316–4.470) | 0.005 | 1.544 (0.814–2.930) | 0.184 |
Pathologic N stage | 174 | 0.010 | |||
N0 | 50 | Reference | Reference | ||
N1 | 124 | 1.746 (1.121–2.720) | 0.014 | 1.453 (0.903–2.340) | 0.124 |
Pathologic M stage | 85 | 0.707 | |||
M0 | 80 | Reference | |||
M1 | 5 | 0.826 (0.296–2.303) | 0.714 | ||
Pathologic stage | 176 | 0.825 | |||
Stage I&Stage II | 168 | Reference | |||
Stage III&Stage IV | 8 | 1.099 (0.480–2.518) | 0.823 | ||
Histologic grade | 177 | 0.018 | |||
G1&G2 | 127 | Reference | Reference | ||
G3&G4 | 50 | 1.671 (1.107–2.523) | 0.015 | 1.488 (0.957–2.314) | 0.077 |
Anatomic neoplasm subdivision | 179 | 0.005 | |||
Head | 139 | Reference | Reference | ||
Body | 14 | 0.403 (0.175–0.928) | 0.033 | 0.670 (0.287–1.564) | 0.355 |
Tail | 15 | 0.824 (0.426–1.594) | 0.566 | 0.749 (0.365–1.537) | 0.430 |
Other | 11 | 0.258 (0.081–0.819) | 0.022 | 0.285 (0.089–0.917) | 0.035 |
History of diabetes | 147 | 0.344 | |||
No | 109 | Reference | |||
Yes | 38 | 0.779 (0.458–1.324) | 0.355 | ||
History of chronic pancreatitis | 142 | 0.727 | |||
No | 129 | Reference | |||
Yes | 13 | 0.880 (0.424–1.828) | 0.731 | ||
Alcohol history | 167 | 0.341 | |||
No | 65 | Reference | |||
Yes | 102 | 1.223 (0.805–1.859) | 0.345 | ||
UPK3B | 179 | 0.001 | |||
Low | 89 | Reference | Reference | ||
High | 90 | 1.887 (1.275–2.792) | 0.001 | 1.534 (1.025–2.298) | 0.038 |
