Table 2 Cluster household characteristics and transmission in the study population by epidemic period, from 2020 to 2023.

From: Natural, vaccine-induced immunity and the probability of experiencing SARS-CoV-2 infection in a household cohort in Rio de Janeiro

Characteristic

Pre-VoC, N = 1421

Gamma/Delta, N = 511

Omicron, N = 791

Cluster with transmission

69 (49%)

17 (33%)

38 (48%)

Median household cluster size (IQR)

4 (2–10)

4 (2–8)

3 (2–9)

Transmissions per cluster

0.8 (0–5)

0.5 (0–4)

0.7 (0–5)

Number of rooms

6.4 (3–18)

6.8 (2–16)

7.0 (3–14)

Persons per room

0.6 (0.2–1.8)

0.7 (0.3–1.6)

0.6 (0.2–1.6)

Children under 12

59 (42%)

22 (43%)

27 (34%)

Adults over 60

56 (39%)

19 (37%)

28 (35%)

Healthcare worker

55 (39%)

17 (33%)

31 (39%)

Average vaccine-induced immunity score2

-

0.6 (0-3.3)

3.6 (1.3-5)

Average infection-induced immunity score3

-

0.4 (0–2)

0.5 (0-1.3)

People with hybrid immunity within the cluster (%)4

-

0.5 (0–25)

2.5 (0-66.7)

  1. 1Mean (Range); n (%)
  2. 2 Score = 0 Unvaccinated
  3. Score = 1 Partially vaccinated with any vaccine
  4. Score = 2 Fully vaccinated > 3 months with CoronaVac or fully vaccinated > 9 months with ChAdOx1-S/nCoV-19 or Ad26.COV2.S
  5. Score = 3 Fully vaccinated < 3 months or booster > 9 months with CoronaVac or fully vaccinated 3 to 9 months or booster > 9 months with ChAdOx1-S/nCoV-19 or Ad26.COV2.S or fully vaccinated or booster > 9 months with BNT162b2
  6. Score = 4 Booster 3 to 9 months with CoronaVac or fully vaccinated < 3 months or booster 3 to 9 months with ChAdOx1-S/nCoV-19 or Ad26.COV2.S or fully vaccinated or booster 3 to 9 months with BNT162b2
  7. Score = 5 Booster < 3 months with CoronaVac, ChAdOx1-S/nCoV-19 or Ad26.COV2.S or fully vaccinated or booster < 3 months with BNT162b2
  8. 3 Score = 0 Not previously infected, Score = 1 Previously infected ≥ 9 months, Score = 2 Previously infected < 9 months
  9. 4We defined the hybrid immunity as the presence of a vaccine-induced immunity score of 4–5 and infection-induced immunity score of 2.