Table 3 Analysis of the potential risk factors associated with household transmission of SARS-CoV-2 by epidemic period, from 2020 to 2023. The values reported in the table are the median parameter estimate and the 95% credible interval.

From: Natural, vaccine-induced immunity and the probability of experiencing SARS-CoV-2 infection in a household cohort in Rio de Janeiro

 

Pre VoC

Gamma/Delta

Omicron

Intercept-only Binomial GLMM

   

Transmission probability (in cluster)

0.179 (0.128–0.229)

0.136 (0.084–0.186)

0.171 (0.134–0.214)

Binomial GLMM (Odds ratios)

   

Variables

   

Household density1

0.663 (0.332–1.321)

0.420 (0.078–2.266)

0.656 (0.225–1.911)

% Children under 12

0.898 (0.588–1.371)

1.650 (0.683–3.988)

1.345 (0.722–2.507)

% Adults over 60

1.222 (0.799–1.869)

0.727 (0.310–1.703)

1.041 (0.556–1.949)

Healthcare worker

0.689 (0.439–1.081)

2.227 (0.952–5.210)

0.486 (0.256–0.921)

SARS-CoV-2 infection-induced immunity score (average)2

-

0.088 (0.023–0.341)

-

% of household members with hybrid immunity3

-

-

0.095 (0.010–0.924)

  1. 1 Household density was defined as the number of residents divided by the number of rooms.
  2. 2 Score = 0 Not previously infected, Score = 1 Previously infected ≥ 9 months, Score = 2 Previously infected < 9 months.
  3. 3 Individuals were classified as having hybrid immunity if they had vaccine-induced and infection-induced immunity within the past 9 months.
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