Table 1 Summary of relevant PK parameters for nicotine (9 measurements per visit (4/648 measurements missed), Cmax and AUC as geometric means with a coefficient of variation (CV in %); tmax as median and range).
Product | Disposable e-cigarette strawberry-kiwi | Disposable e-cigarette tobacco | Cigarette | Pod e-cigarette |
|---|---|---|---|---|
Cmax (ng/mL) | 7.1 (168%) | 6.9 (155%) | 8.1 (159%) | 3.1 (141%) |
tmax (min) | 5 (1–10) | 6 (2–10) | 8 (4–30) | 6 (1–12) |
AUC0−30 min (ng/mL×h) | 111.3 (143%) | 110.6 (126%) | 148.1 (141%) | 58.3 (148%) |