Table 1 Patient characteristics by sex.

From: Factors related to sex differences in long-term functional decline after acute ischemic stroke

 

Women

Men

P

n = 2691

n = 4157

Age

 Age, y, mean ± SD

72.0 ± 12.3

67.1 ± 11.4

 < 0.001

 Old age, n (%)

1291 (48.0)

1140 (27.4)

 < 0.001

Body weight

 Body mass index, kg/m2, mean ± SD

23.1 ± 4.0

23.9 ± 3.3

 < 0.001

 Underweight, n (%)

245 (9.1)

130 (3.1)

 < 0.001

 Obesity, n (%)

737 (27.4)

1359 (32.7)

 < 0.001

Risk factors and comorbidities, n (%)

 Hypertension

2125 (79.0)

3320 (79.9)

0.37

 Diabetes mellitus

667 (24.8)

1390 (33.4)

 < 0.001

 Dyslipidemia

1688 (62.7)

2302 (55.4)

 < 0.001

 Atrial fibrillation

464 (17.2)

741 (17.8)

0.54

 Smoking

444 (16.5)

3246 (78.1)

 < 0.001

 Drinking

342 (12.7)

2327 (56.0)

 < 0.001

 Ischemic heart disease

303 (11.3)

595 (14.3)

 < 0.001

 Chronic kidney disease

857 (31.8)

1183 (28.5)

0.003

Stroke characteristics, n (%)

 Previous history of stroke

431 (16.0)

782 (18.8)

0.003

 Cardioembolic stroke

426 (15.8)

618 (14.9)

0.28

 Severe stroke

444 (16.5)

456 (11.0)

 < 0.001

Neurological impairment, n (%)

 Arm weakness

627 (23.3)

651 (15.7)

 < 0.001

 Leg weakness

624 (23.2)

625 (15.0)

 < 0.001

 Limb weakness

755 (28.1)

809 (19.5)

 < 0.001

 Aphasia

285 (10.6)

321 (7.7)

 < 0.001

Medication, n (%)

 Antihypertensives

1409 (52.4)

2171 (52.2)

0.91

 Antidiabetics

490 (18.2)

1019 (24.5)

 < 0.001

 Antidyslipidemics

1517 (56.4)

2005 (48.2)

 < 0.001

 Antiplatelets

2013 (74.8)

3252 (78.2)

0.001

 Anticoagulants

730 (27.1)

1093 (26.3)

0.45

Functional status at 3 months

 3-month mRS score, median (IQR)

1 (0–3)

1 (0–2)

 < 0.001

 Functional dependency, n (%)

754 (28.0)

566 (13.6)

 < 0.001

  1. SD, standard deviation; mRS, modified Rankin Scale; IQR, interquartile range.
  2. Old age was defined as age ≥ 75 years at the onset of the index stroke. Underweight and obesity were defined as body mass index < 18.5 and ≥ 25 kg/m2, respectively. Severe stroke was defined as an National Institutes of Health Stroke Scale score on admission ≥ 8. Functional dependency was defined as an mRS score of 3‒5.