Table 3 Clinical and AMI-treatment-related data (1) in patients with and without early depressive symptoms 5 days after AMI; (2) in patients with and without depression 6 months after AMI; and 3) in depressive patients with and without comorbid PTSD 6 months after AMI.
Category | 5 days after acute myocardial infarction | 6 months after acute myocardial infarction | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Patients with early depressive symptoms | Patients without early depressive symptoms | p | Patients with depression | Patients without depression | P | Depressive patients with comorbid PTSD | Depressive patients without comorbid PTSD | P | ||
(n = 55) | (n = 74) | (n = 67) | (n = 62) | (n = 44) | (n = 23) | |||||
Anthropometry | ||||||||||
Height (cm) | Median (Range) | 176 (152 − 19) | 175 (155–196) | .52d | 175 (155–196) | 176 (152–191) | .27d | 174 (155–185) | 175,5 (162–196) | .16d |
Weight (kg) | Median (Range) | 86 (54–119) | 85 (53–132) | .96d | 85 (53–132) | 85 (54–119) | .99d | 87 (53–132) | 84,5 (65–128) | .96d |
Cardiac status at time of admission | ||||||||||
STEMI | n (%) | 35 (43%) | 47 (47%) | > .99a | 42 (51%) | 40 (49%) | .86a | 25 (60%) | 17 (40%) | .20a |
NSTEMI | n (%) | 20 (43%) | 27 (57%) | 25 (53%) | 22 (47%) | 19 (76%) | 6 (24%) | |||
Killip mortality risk stratification | ||||||||||
Killip class I | n (%) | 41 (41%) | 60 (59%) | χ² = 4.221; p = .24c, e | 52 (51%) | 49 (49%) | χ² = 2.762; p = .43c, e | 35 (67%) | 17 (33%) | χ² = 1.096,; p = .78c, e |
Killip class II | n (%) | 5 (63%) | 3 (38%) | 5 (63%) | 3 (38%) | 3 (60%) | 2 (40%) | |||
Killip class III | n (%) | 3 (50%) | 3 (50%) | 3 (50%) | 3 (50%) | 2 (67%) | 1 (33%) | |||
Killip class IV | n (%) | 2 (100%) | 0 (0%) | 2 (100%) | 0 (0%) | 2 (100%) | 0 (0%) | |||
Abnormal level of troponin T | n (%) | 55 (43%) | 74 (57%) | - | 67 (52%) | 62 (48%) | - | 44 (66%) | 23 (34%) | - |
Cardiogenic shock | n (%) | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - |
AMI-related resuscitation | n (%) | 3 (75%) | 1 (25%) | .31a | 3 (75%) | 1 (25%) | .62a | 3 (100%) | 0 (0%) | .55a |
ECG: Frequency (beats/min) | Median (Range) | 70 (46–104) | 72 (52–108) | .53d | 70 (46–106) | 73,5 (52–108) | .57d | 70 (46–106) | 70 (50–104) | .86d |
ECG: Atrial fibrillation | n (%) | 5 (62%) | 3 (38%) | .28a | 6 (75%) | 2 (25%) | .27a | 3 (50%) | 3 (50%) | .41a |
PCI-related parameters | ||||||||||
TIMI flow before PCI | ||||||||||
0 | n (%) | 8 (62%) | 5 (38%) | χ² = 1.415; p = .70c, e | 7 (54%) | 6 (46%) | χ² = 5.739; p = .057c, e | 3 (43%) | 4 (57%) | χ² = 2.100,; p = .55c, e |
0-I | n (%) | 50 (55%) | 41 (45%) | 48 (53%) | 43 (47%) | 32 (67%) | 16 (33%) | |||
II | n (%) | 12 (60%) | 8 (40%) | 8 (40%) | 12 (60%) | 6 (75%) | 2 (25%) | |||
III | n (%) | 4 (80%) | 1 (20%) | 4 (80%) | 1 (20%) | 3 (75%) | 1 (25%) | |||
TIMI flow after PCI | ||||||||||
0 | n (%) | 0 (-) | 0 (-) | χ² = 5.739; p = .057c, e | 0 (-) | 0 (-) | χ² = 1.601; p = .45c, e | 0 (-) | 0 (-) | χ² = 3.365; p = .76c, e |
0-I | n (%) | 4 (80%) | 1 (20%) | 1 (20%) | 4 (80%) | 1 (100%) | 0 (0%) | |||
II | n (%) | 2 (22%) | 7 (78%) | 8 (89%) | 1 (11%) | 5 (63%) | 3 (37%) | |||
III | n (%) | 68 (59%) | 47 (41%) | 58 (50%) | 57 (50%) | 38 (66%) | 20 (34%) | |||
Multivessel PCI | n (%) | 11 (41%) | 16 (59%) | .52a | 16 (59%) | 11 (41%) | χ² = 1.601, p = .45c | 12 (75%) | 4 (25%) | .55a |
Max. stent length in the target vessel (mm) | Median (Range) | 28 (12–126) | 26 (10–82) | .29d | 28 (13–126) | 25 (10–82) | .35d | 28 (13–126) | 28 (15–72) | .95d |
Max. stent diameter in the target vessel (mm) | Median (Range) | 300 (250–400) | 300 (100–400) | > .99d | 300 (250–400) | 300 (100–400) | .56d | 300 (250–400) | 300 (250–400) | .50d |
In-hospital outcome | ||||||||||
Death | n (%) | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - |
Stroke | n (%) | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - |
Major bleeding | n (%) | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - | 0 (-) | 0 (-) | - |
Reinfarction | n (%) | 0 (0%) | 2 (100%) | .51a | 0 (0%) | 2 (100%) | χ² = 2.812, p = .25c | 0 (-) | 0 (-) | - |
Left-ventricular ejection fraction (%) | Median (Range) | 55 (15–70) | 50 (30–70) | .30d | 54,5 (15–70) | 50 (30–70) | .45d | 53 (15–70) | 54,5 (15–70) | .47d |
Cardiac risk factors | ||||||||||
Known coronary artery disease | n (%) | 10 (45%) | 12 (55%) | > .99a | 16 (73%) | 6 (27%) | .06a | 11 (69%) | 5 (31%) | > .99a |
Nicotine abuse | n (%) | 28 (47%) | 31 (53%) | .31a | 29 (49%) | 30 (51%) | .60a | 20 (69%) | 9 (31%) | .80a |
Peripheral arterial occlusive disease | n (%) | 2 (50%) | 2 (50%) | > .99a | 3 (75%) | 1 (25%) | .62a | 3 (100%) | 0 (0%) | 0.55a |
IDDM | n (%) | 1 (50%) | 1 (50%) | > .99a | 2 (100%) | 0 (0%) | .50a | 1 (50%) | 1 (50%) | > .99a |
NIDDM | n (%) | 6 (32%) | 13 (68%) | .33a | 12 (63%) | 7 (37%) | .33a | 10 (83%) | 2 (17%) | .20a |
Hypertension | n (%) | 48 (42%) | 67 (58%) | .58a | 58 (50%) | 57 (50%) | .40a | 36 (62%) | 22 (38%) | .15a |
Hyperlipidemia | n (%) | 34 (49%) | 35 (51%) | .15a | 41 (59%) | 28 (41%) | .15a | 27 (66%) | 14 (34%) | > .99a |
Positive family history | n (%) | 12 (50%) | 12 (50%) | .64a | 12 (50%) | 12 (50%) | > .99a | 7 (58%) | 5 (42%) | .48a |
History of myocardial infarction | n (%) | 7 (50%) | 7 (50%) | .58a | 11 (79%) | 3 (21%) | 0.047a | 9 (82%) | 2 (18%) | .48a |
Severe liver disease | n (%) | 2 (67%) | 1 (33%) | .58a | 1 (33%) | 2 (67%) | .61a | 0 (0%) | 1 (100%) | .34a |
History of TIA or Stroke | n (%) | 2 (50%) | 2 (50%) | > .99a | 3 (75%) | 1 (25%) | .62a | 1 (33%) | 2 (67%) | .26a |