Fig. 7
Key gene-related miRNA network and transcriptional regulatory network. (a) The miRNA network of key genes, with ellipses representing mRNA and inverted triangles representing miRNA. It can be seen that there is a correlation between key genes and miRNAs, and miR-214, miR-146ac, etc. are considered as key miRNAs. (b) The transcriptional regulatory network of key genes, with green representing key genes and red representing transcription factors. The correlation between key genes and transcription factors can be observed, indicating that FOXO1 is considered a key transcription factor. (c) All enriched motifs and corresponding transcription factors of key genes were displayed. You can clearly see the motif numbers, corresponding standardized enrichment scores, and transcription factors. The highest standardized enrichment score is cisbp__M5578.
