Table 4 Antimicrobial susceptibility profiles of GNB isolates among neonates suspected of omphalitis.

From: Bacterial profile, antibiotic susceptibility patterns and associated factors among neonates suspected of omphalitis in Arba Minch, Southern Ethiopia

Classes

Antibiotics

AMST

GNB % (n)

Total

EC (n = 39)

KP (n = 6)

KO

(n = 4)

PM (n = 9)

PV (n = 4)

EF (n = 8)

n = 70

β-Lactam/β-lactamase

inhibitor combinations

Amoxicillin-clavulanate

S

23 (59)

3 (50)

2 (50)

5 (55.6)

2 (50.0)

4 (50.0)

39 (55.7)

R

16 (41)

3 (50)

2 (50)

4 (44.4)

2 (50)

4 (50.0)

31 (44.3)

Third and fourth generation of Cephalosporins

Ceftriaxone

S

17 (43.6)

2 (33.3)

2 (50)

5 (55.6)

2 (50)

6 (75.0)

34 (48.6)

R

22 (56.4)

4 (66.7)

2 (50)

4 (44.4)

2 (50)

2 (25.0)

36 (51.4)

Cefotaxime

S

23 (59)

3 (50)

2 (50)

6 (66.7)

3 (75.0)

5 (62.5)

42 (60)

R

16 (41)

3 (50)

2 (50)

3 (33.3)

1 (25.0)

3 (37.5)

28 (40)

Cefepime

S

36 (92.3)

6 (100)

4 (100)

9 (100)

4 (100)

6 (75.0)

65 (92.8)

R

3 (8.7)

0 (0)

0 (0)

0 (0)

0 (0)

2 (25.0)

5 (7.2)

Carbapenem

Meropenem

S

32 (82.0)

5 (83.7)

4 (100)

7 (77.8)

4 (100)

6 (75.0)

58 (82.9)

R

7 (18.0)

1 (16.3)

0 (0)

2 (22.2)

0 (0)

2 (25.0)

12 (17.1)

Quinolones

Ciprofloxacin

S

25 (64.1)

5 (83.3)

3 (75)

6 (66.7)

3 (75.0)

6 (75.0)

48 (68.5)

R

14 (35.9)

1 (16.7)

1 (25)

3 (33.3)

1 (25.0)

2 (25.0)

22 (31.5)

Amphenicol

Chloramphenicol

S

25 (64.1)

5 (83.3)

3 (75)

5 (55.6)

4 (100)

5 (62.5)

47 (67.1)

R

14 (35.9)

1 (16.7)

1 (25)

4 (44.4)

0 (0)

3 (37.5)

23 (32.9)

Aminoglycosides

Gentamicin

S

24 (61.5)

4 (66.7)

3 (75)

6 (66.7)

3 (75.0)

5 (62.5)

45 (64.3)

R

15 (38.5)

2 (33.3)

1 (25)

3 (33.3)

1 (25.0)

3 (37.5)

25 (35.7)

Amikacin

S

24 (61.5)

5 (83.3)

4 (100)

6 (66.7)

1 (25.0)

4 (50)

44 (62.8)

R

15 (38.5)

1 (16.7)

0 (0)

3 (33.3)

3 (75.0)

4 (50)

26 (37.2)

Tetracycline

Tetracycline

S

16 (41.0)

3 (50)

2 (50)

3 (33.3)

1 (25.0)

4 (50)

29 (41.4)

R

23 (59.0)

3 (50)

2 (50)

6 (66.7)

3 (75.0)

4 (50)

41 (58.6)

Folate pathway inhibitors

Sulfamethoxazole-trimethoprim

S

21 (53.8)

4 (66.7)

2 (50)

4 (44.4)

2 (50.0)

4 (50)

37 (52.9)

R

18 (46.2)

2 (33.3)

2 (50)

5 (55.6)

2 (50.0)

4 (50)

33 (47.1)

  1. EC: E. coli, KP: K. pneumoniae, KO: K. oxytoca, PM: P. mirabilis, PV: P. vulgaris, EA: E. aerogenes, S: susceptible, R: resistant, ND: Not done, SXT: sulfamethoxazole-trimethoprim, CTX: cefotaxime, CTR: ceftriaxone, CHL: chloramphenicol, GEN: gentamicin, TET: tetracycline, AMK: amikacin, CPR: ciprofloxacin, AMC: amoxicillin-clavulanate, MEM: meropenem, CEP: cefepime.
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