Table 5 Antimicrobial susceptibility patterns of GPB from neonates with omphalitis.

From: Bacterial profile, antibiotic susceptibility patterns and associated factors among neonates suspected of omphalitis in Arba Minch, Southern Ethiopia

Classes

Antibiotics

AMST

GPC

Total

(n = 71)

S. aureus (n = 41)

CoNs (n = 16)

S. pyogenes

(n = 7)

E. faecalis (n = 7)

Penicillin

Penicillin

S

6 (14.6)

6 (37.5)

7 (100)

2 (28.6)

21 (29.5)

R

35 (85.4)

10 (62.5)

0 (0)

5 (71.4)

50 (70.4)

Cloxacillin

S

19 (46.3)

7 (43.8)

3 (42.9)

3 (42.9)

32 (45.1)

R

22 (53.7)

9 (56.2)

4 (57.1)

4 (57.1)

39 (54.9)

Aminopenicillin

Ampicillin

S

ND

ND

2 (28.6)

2 (28.6)

4 (28.6)

R

ND

ND

5 (71.4)

5 (71.4)

10 (71.4)

β-Lactam/β-lactamase

inhibitor combinations

Amoxicillin-clavulanate

S

ND

13 (81.3)

ND

ND

13 (81.3)

R

ND

3 (18.7)

ND

ND

3 (18.7)

Glycopeptides

Vancomycin

S

ND

ND

ND

7 (100)

7 (100)

R

ND

ND

ND

0 (0)

0 (0)

Cephalosporin

Cefoxitin

S

27 (65.9)

10 (62.5)

ND

ND

37 (64.9)

R

14 (34.1)

6 (37.5)

ND

ND

20 (35.1)

Macrolides

Erythromycin

S

26 (63.4)

10 (62.5)

5 (71.4)

5 (71.4)

46 (64.8)

R

15 (36.6)

6 (37.5)

2 (28.6)

2 (28.6)

25 (35.2)

Amphenicol

Chloramphenicol

S

27 (65.9)

10 (62.5)

5 (71.4)

5 (71.4)

47 (66.2)

R

14 (34.1)

6 (37.5)

2 (28.6)

2 (28.6)

24 (34.8)

Lincosamides

Clindamycin

S

37 (90.2)

13 (81.3)

ND

ND

50 (87.7)

R

4 (9.8)

3 (12.5)

ND

ND

7 (12.3)

Quinolones

Ciprofloxacin

S

28 (68.3)

12 (75)

ND

ND

40 (70.2)

R

13 (31.7)

4 (25)

ND

ND

17 (29.8)

Tetracycline

Tetracycline

S

13 (31.7)

8 (50)

ND

ND

21 (36.8)

R

28 (68.3)

8 (50)

ND

ND

36 (63.2)

Folate pathway inhibitors

Sulfamethoxazole-trimethoprim

S

14 (34.1)

6 (37.5)

ND

ND

20 (35.1)

R

27 (65.9)

10 (62.5)

ND

ND

37 (64.9)

  1. S: susceptible, R: resistant, ND: Not done, PEN: penicillin, CXT: cefoxitin, CHL: chloramphenicol, ERY: erythromycin, TET: tetracycline, CPR: ciprofloxacin, VAN: vancomycin, SXT-sulfamethoxazole-trimethoprim, AMC: amoxicillin-clavulanate, AMP: ampicillin, CLN: clindamycin. *ND corresponds to a change in the denominator (total number of isolates tested).