Table 2 The association of each inflammatory indicator with in-hospital mortality.

From: The effect of inflammatory markers on mortality in patients with acute myocardial infarction

Category

Model I

Model II

Model III

OR (95% CI)

P

P for trend

OR (95% CI)

P

P for trend

OR (95% CI)

P

P for trend

Continuous RDW

 

1.18 (1.14, 1.23)

< 0.001

 

1.15 (1.11, 1.20)

< 0.001

 

1.07 (1.01, 1.13)

0.025

 

Quartiles of RDW

Q1 (N = 734)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.003

Q2 (N = 687)

1.73 (1.19, 2.51)

0.004

 

1.52 (1.04, 2.21)

0.030

 

0.98 (0.62, 1.56)

0.930

 

Q3 (N = 662)

2.88 (2.03, 4.08)

< 0.001

 

2.38 (1.66, 3.41)

< 0.001

 

1.58 (1.01, 2.48)

0.047

 

Q4 (N = 701)

4.66 (3.34, 6.50)

< 0.001

 

3.74 (2.65, 5.28)

< 0.001

 

1.96 (1.21, 3.17)

0.006

 

Continuous NLR

 

1.03 (1.02, 1.04)

< 0.001

 

1.03 (1.02, 1.03)

< 0.001

 

1.01 (1.00, 1.02)

0.024

 

Quartiles of NLR

Q1 (N = 696)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.094

Q2 (N = 696)

1.32 (0.92, 1.92)

0.136

 

1.31 (0.91, 1.91)

0.151

 

1.19 (0.76, 1.86)

0.440

 

Q3 (N = 696)

2.36 (1.68, 3.31)

< 0.001

 

2.14 (1.52, 3.02)

< 0.001

 

1.46 (0.97, 2.21)

0.073

 

Q4 (N = 696)

3.98 (2.88, 5.50)

< 0.001

 

3.51 (2.53, 4.87)

< 0.001

 

1.63 (1.08, 2.47)

0.019

 

Continuous PLR

 

1.01 (1.00, 1.02)

< 0.001

 

1.00 (1.00, 1.01)

< 0.001

 

1.00 (1.00, 1.00)

0.462

 

Quartiles of PLR

Q1 (N = 696)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.028

Q2 (N = 696)

1.18 (0.84, 1.65)

0.343

 

1.12 (0.79, 1.57)

0.532

 

1.07 (0.70, 1.62)

0.761

 

Q3 (N = 696)

2.02 (1.47, 2.76)

< 0.001

 

2.00 (1.46, 2.75)

< 0.001

 

1.70 (1.13, 2.55)

0.010

 

Q4 (N = 696)

2.27 (1.67, 3.09)

< 0.001

 

1.99 (1.45, 2.72)

< 0.001

 

1.42 (0.95, 2.13)

0.086

 

Continuous MLR

 

1.47 (1.32, 1.62)

< 0.001

 

1.40 (1.27, 1.55)

< 0.001

 

1.11 (0.98, 1.24)

0.084

 

Quartiles of MLR

Q1 (N = 698)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.103

Q2 (N = 694)

1.27 (0.89, 1.82)

0.192

 

1.18 (0.83, 1.70)

0.358

 

1.12 (0.71, 1.76)

0.624

 

Q3 (N = 696)

2.15 (1.54, 2.99)

< 0.001

 

1.85 (1.32, 2.59)

< 0.001

 

1.56 (1.02, 2.38)

0.040

 

Q4 (N = 696)

3.41 (2.49, 4.68)

< 0.001

 

2.87 (2.07, 3.96)

< 0.001

 

1.48 (0.98, 2.24)

0.052

 

Continuous RPR

 

19.24 (7.65, 48.37)

< 0.001

 

14.44

(5.63, 27.04)

< 0.001

 

9.02

(2.21, 16.90)

0.002

 

Quartiles of RPR

Q1 (N = 698)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.348

Q2 (N = 694)

1.13 (0.83, 1.55)

0.444

 

1.16 (0.84, 1.60)

0.365

 

1.15 (0.72, 1.84)

0.564

 

Q3 (N = 696)

1.00 (0.72, 1.38)

0.984

 

0.96 (0.69, 1.33)

0.808

 

0.74 (0.48, 1.12)

0.156

 

Q4 (N = 696)

2.22 (1.66, 2.96)

< 0.001

 

1.94 (1.44, 2.60)

< 0.001

 

0.89 (0.54, 1.45)

0.631

 

Continuous SII

 

1.00 (1.00, 1.01)

< 0.001

 

1.00 (1.00, 1.01)

< 0.001

 

1.04 (1.01, 1.11)

0.042

 

Quartiles of SII

Q1 (N = 696)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

0.007

Q2 (N = 696)

0.93 (0.65, 1.31)

0.659

 

0.91 (0.64, 1.30)

0.614

 

1.01 (0.66, 1.55)

0.955

 

Q3 (N = 696)

1.49 (1.09, 2.05)

0.013

 

1.43 (1.04, 1.97)

0.029

 

1.14 (0.76, 1.71)

0.541

 

Q4 (N = 696)

2.76 (2.05, 3.71)

< 0.001

 

2.51 (1.86, 3.39)

< 0.001

 

1.85 (1.21, 2.85)

0.005

 

Continous SIRI

 

1.00 (1.00, 1.01)

< 0.001

 

1.00 (1.00, 1.01)

< 0.001

 

1.00 (0.89, 1.03)

0.290

 

Quartiles of SIRI

Q1 (N = 696)

Ref

 

< 0.001

Ref

 

< 0.001

Ref

 

< 0.001

Q2 (N = 696)

1.41 (0.97, 2.06)

0.072

 

1.28 (0.88, 1.88)

0.198

 

1.10 (0.70, 1.73)

0.680

 

Q3 (N = 696)

3.24 (2.31, 4.55)

< 0.001

 

2.79 (1.98, 3.94)

< 0.001

 

1.79 (1.17, 2.74)

0.007

 

Q4 (N = 696)

3.68 (2.63, 5.16)

< 0.001

 

3.53 (2.51, 4.95)

< 0.001

 

2.23 (1.42, 3.50)

< 0.001

 
  1. Mode I: unadjusted; model II: adjusted by age, sex, heart rate, and oxygen saturation; model III: model II further adjusted by hypertension, atrial fibrillation, congestive heart failure, cerebrovascular disease, kidney disease, liver disease, peripheral vascular disease, malignant tumor, red blood cell counts, white blood cell counts, hemoglobin, platelet counts, creatinine, blood Urea nitrogen, electrolytes, glucose, total bilirubin, plasma prothrombin time, acute physiology score III, Oxford acute severity score, Sepsis-Related organ failure assessment score, systemic inflammatory response score system, coronary artery bypass grafting, aspirin, Statins, β-blockers, angiotensin converting enzyme inhibitors/angiotensin receptor blockers, calcium channel blockers, nitrates. OR, odds ratio; CI, confidence interval; Q, quartile; ref, reference; RDW, red blood cell distribution width; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; MLR, monocyte to lymphocyte ratio; RPR, red blood cell volume distribution width to platelet ratio; SII, systemic immune inflammation index; SIRI, systemic inflammatory response index.
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