Table 1 Clinical characteristics and outcomes of acute ischemic stroke patients stratified by 90-Day functional outcome after mechanical thrombectomy.
Variables | 90-day functional outcome | P value | ||
|---|---|---|---|---|
Overall, N = 421 | mRS 0–2, N = 167 | mRS 3–6, N = 254 | ||
Baseline Characteristics | ||||
Age, year | 68 (57, 76) | 64 (55, 72) | 69 (59, 78) | < 0.001 |
Male sex, n (%) | 283 (67.22) | 116 (69.46) | 167 (65.75) | 0.427 |
Current smoker, n (%) | 151 (35.87) | 69 (41.32) | 82 (32.28) | 0.059 |
Alcohol consumption, n (%) | 95 (22.57) | 42 (25.15) | 53 (20.87) | 0.304 |
Medical history, n (%) | ||||
Hypertension | 289 (68.65) | 110 (65.87) | 179 (70.47) | 0.319 |
Diabetes mellitus | 125 (29.69) | 41 (24.55) | 84 (33.07) | 0.061 |
Hyperlipidemia | 99 (23.52) | 49 (29.34) | 50 (19.69) | 0.022 |
Previous stroke or TIA | 66 (15.68) | 24 (14.37) | 42 (16.54) | 0.550 |
Coronary heart disease | 54 (12.83) | 16 (9.58) | 38 (14.96) | 0.106 |
Atrial fibrillation | 173 (41.09) | 56 (33.53) | 117 (46.06) | 0.011 |
Valvular heart disease | 51 (12.11) | 19 (11.38) | 32 (12.60) | 0.707 |
Initial Clinical Assessment | ||||
Baseline NIHSS score | 15 (11, 19) | 13 (8, 16) | 17 (13, 20) | < 0.001 |
Baseline GCS score | 12 (10, 14) | 14 (11, 15) | 11 (9, 14) | < 0.001 |
Systolic blood pressure, mmHg | 148 (133, 163) | 148 (133, 161) | 147 (132, 164) | 0.726 |
Diastolic blood pressure, mmHg | 87 (77, 97) | 87 (77, 98) | 88 (77, 96) | 0.874 |
Stroke etiology, n (%) | 0.168 | |||
Large-artery atherosclerosis | 217 (51.54) | 95 (56.89) | 122 (48.03) | |
Cardioembolism | 185 (43.94) | 64 (38.32) | 121 (47.64) | |
Others | 19 (4.51) | 8 (4.79) | 11 (4.33) | |
Occluded vessel, n (%) | 0.085 | |||
Anterior circulation | 346 (82.19) | 141 (84.43) | 205 (80.71) | |
Posterior circulation | 68 (16.15) | 26 (15.57) | 42 (16.54) | |
Both anterior and posterior | 7 (1.66) | 0 (0.00) | 7 (2.76) | |
Procedural Characteristics, n (%) | ||||
Intravenous thrombolysis | 170 (40.38) | 71 (42.51) | 99 (38.98) | 0.469 |
Onset to puncture time, min | 378 (264, 600) | 367 (237, 655) | 388 (276, 584) | 0.432 |
Onset to reperfusion time, min | 498 (365, 738) | 490 (327, 749) | 500 (379, 732) | 0.421 |
Puncture to reperfusion time, min | 97 (60, 155) | 95 (55, 142) | 98 (65, 165) | 0.124 |
Number of thrombectomy attempts | 2.00 (1.00, 2.00) | 1.00 (1.00, 2.00) | 2.00 (1.00, 3.00) | 0.003 |
Successful reperfusion | 160 (38.00) | 73 (43.71) | 87 (34.25) | 0.050 |
Treatment Strategy, n (%) | ||||
Thrombectomy alone | 104 (24.70) | 43 (25.75) | 61 (24.02) | 0.687 |
Aspiration alone | 24 (5.70) | 9 (5.39) | 15 (5.91) | 0.823 |
Combined approach | 259 (61.52) | 103 (61.68) | 156 (61.42) | 0.957 |
Balloon angioplasty | 86 (20.43) | 38 (22.75) | 48 (18.90) | 0.337 |
Clinical Outcomes, n (%) | ||||
Hemorrhagic transformation | 197 (46.79) | 51 (30.54) | 51 (30.54) | < 0.001 |
sICH | 76 (18.05) | 3 (1.80) | 73 (28.74) | < 0.001 |
Discharge mRS | 4.00 (2.00, 5.00) | 2.00 (1.00, 3.00) | 5.00 (4.00, 5.00) | < 0.001 |
90-day mRS | 3.00 (1.00, 5.00) | 1.00 (0.00, 2.00) | 4.00 (4.00, 6.00) | < 0.001 |
