Table 2 Limb and lesion characteristics.

Limb and lesion characteristics	Lesion length > 15 cm N = 115^a	Lesion length ≤ 15 cm N = 141^a	p - value
Bilateral disease ^b, % (n/N)	86.1 (99/115)	77.3 (109/141)	0.073
ABI, per target limb, mm Hg, (mean ± SD)	0.29 ± 0.27	0.42 ± 0.29	0.002
Occlusion, % (n/N)	90.4 (104/115)	53.9 (76/141)	< 0.001
Lesion type, % (n/N)			0.038
De novo	68.7 (79/115)	82.3 (116/141)	0.011
Restenotic (nonstented)	8.7 (10/115)	5.7 (8/141)	0.347
In-stent restenosis	22.6 (26/115)	12.1 (17/141)	0.025
Calcification, % (n/N)			0.550
None	44.3 (51/115)	51.1 (72/141)	0.285
Mild	43.5 (50/115)	39.0 (55/141)	0.469
Severe	12.2 (14/115)	9.9 (14/141)	0.567
Below-the-knee outflow, % (n/N)			0.271
None	6.1 (7/115)	9.9 (14/141)	0.265
1 vessel	34.8 (40/115)	29.8 (42/141)	0.394
2 vessels	41.7 (48/115)	35.5 (50/141)	0.304
3 vessels	17.4 (20/115)	24.8 (35/141)	0.150
Rutherford Clinical Category, % (n/N)			0.110
3	45.9 (51/111)	55.4 (77/139)	0.087
4	26.1 (29/111)	28.8 (40/139)	0.374
5	25.2 (28/111)	15.1 (21/139)	0.033
6	2.7 (3/111)	0.7 (1/139)	0.232
TASC II, % (n/N)			< 0.001
A	0	36.9 (52/141)	< 0.001
B	0	61.7 (87/141)	< 0.001
C	45.2 (52/115)	0.7 (1/141)	< 0.001
D	54.8 (68/115)	0.7 (1/141)	< 0.001
Atherectomy, % (n/N)	5.2 (6/115)	4.3 (6/141)	0.717
Bailout stenting, % (n/N)	15.7 (18/115)	9.9 (14/141)	0.168
Dissection	8.7 (10/115)	7.1 (10/141)	0.634
Residual stenosis	5.2 (6/115)	2.1 (3/141)	0.306
Dissection + Residual stenosis	1.7 (2/115)	0.7 (1/141)	0.589

Data are expressed as mean ± standard deviation (SD) or % (n/N). ABI ankle-brachial index; ISR in-stent restenosis; DCB drug-coated balloon.
^a Summaries are based on no missing assessments. In some cases, due to lack of baseline data or reclassification within a subgroup, the total number of lesions was less than 115 and 141.
^b Bilateral disease is defined as stenosis or restenosis of both lower limb vessels (< 50% residual lumen diameters in the target lesion under CTA, or peak systolic velocity ratio ≤ 2.4 under Doppler ultrasound examination).

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