Fig. 3
From: Targeted metabolomic evaluation of peripheral blood mononucleated cells from patients with PMM2-CDG

Nicotinic coenzyme ratios and acetyl-CoA in PBMCs of controls and PMM2-CDG patients. NAD+/NADH ratio (A), NADP+/NADPH ratio (B) and acetyl-CoA (C) determined in PBMCs obtained from control healthy subjects and PMM2-CDG patients. Values of the nicotinic coenzyme ratios of PBMCs of controls and PMM2-CDG patients were calculated using the actual concentrations of NAD+ , NADH, NADP+ and NADPH determined in each sample. Mean values and standard deviations are indicated by vertical bars. *Significantly different from controls, p < 0.01. **Significantly different from controls, p < 0.02.