Fig. 1 | Scientific Reports

Fig. 1

From: A model workflow for microfluidic enrichment and genetic analysis of circulating melanoma cells

Fig. 1

Workflow for CMC enrichment and genetic characterization. Blood from melanoma patients was processed through the CellSearch platform and/or the Parsortix system equipped with a customized antibody cocktail. DNA derived from harvested CMCs, superamplified or not, was analyzed with a customized NGS panel, ddPCR and MLPA to identify tumor genetic alterations. Paired cfDNA was used to assess/validate the genetic alterations identified in CMCs. The figure was created with BioRender (https://biorender.com/).

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