Fig. 7 | Scientific Reports

Fig. 7

From: FG-4592 combined with PRP significantly accelerates the healing of refractory diabetic wounds by upregulating HIF-1α

Fig. 7

Summary diagram of the mechanism of action of FG-4592 and PRP in diabetic wound healing. The figure was created in Fig Draw (www.figdraw.com). FG-4592 and PRP accelerated diabetic wound healing by upregulation of the expression of HIF-1α and its target gene expression, reversing the effects of high glucose levels on EPC recruitment, neovascularization, collagen deposition and cell proliferation and migration.

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