Fig. 6 | Scientific Reports

Fig. 6

From: Consequences of vitamin D deficiency or overdosage on follicular development and steroidogenesis in Normo and hypo calcemic mouse models

Fig. 6

Cross-sections of ovarian tissue from different groups; the cross-section from the control group represented the normal distribution of follicles at different stages along with distributed corpus luteums from the previous cycles in the cortex area. See the expanded follicular atresia in the sections from the experimental groups at various stages of the folliculogenesis. The intact follicles contain normal oocytes (NO), with homogenous cytoplasm without cytoplasmic vacuolation (CV), well-formed theca layers (black arrow), and normal integrity of granulosa cells (NGC) with no granulosa cell dissociation (GCD) and antrum formation (*), no hyalinization (HCG), normal cumulus oophorus integrity (NCOI) with no apoptotic granulosa cells (AGC) when compared to the atretic follicles (H&E staining, the photomicrographs with higher magnifications: 400× microscopic and 2.4× optical magnification).

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