Table 1 Baseline characteristics.

From: The efficiency of azelastine hydrochloride and fluticasone propionate nasal spray to improve PAP adherence in patients with obstructive sleep apnea

Characteristic

Active

Placebo

Age ≥ 60, year old (%)

11 (18.6)

8 (14.0)

Age < 60, year old (%)

48 (81.4)

49 (86.0)

Body weight, kg, mean (SD)

91.4 (24.5)

89.7 (21.2)

Height, cm, mean (SD)

166.9 (13.1)

164.4 (7.9)

BMI, kg/m2, mean (SD)

31.9 (7.9)

33.1 (7.2)

Sex

 Male, n (%)

34 (57.6)

32 (56.1)

 Female, n (%)

25 (42.4)

25 (43.9)

Active smoker, n (%)

7 (11.9%)

7 (12.3%)

Education

 Primary education, n (%)

3 (5.1)

6 (10.5)

 Secondary education, n (%)

10 (16.9)

12 (21.1)

 Bachelor’s degree, n (%)

40 (67.8)

38 (66.7)

 Master’s degree, n (%)

6 (10.2)

1 (1.8)

 Doctoral Degree, n (%)

0 (0.0)

0 (0.0)

Healthcare scheme

 Universal Coverage Scheme, n (%)

12 (20.3)

4 (7.0)

 Social Security Scheme, n (%)

5 (8.5)

5 (8.8)

 Government Officer Scheme, n (%)

42 (71.2)

48 (84.2)

Occupation

 Government officer, n (%)

29 (49.2)

33 (57.9)

 Merchant, n (%)

6 (10.2)

7 (12.3)

 Business owner, n (%)

7 (11.9)

5 (8.8)

 Healthcare worker, n (%)

9 (15.3)

6 (10.5)

 Office worker, n (%)

4 (6.8)

6 (10.5)

 Unemployed/Retired, n (%)

4 (6.8)

1 (1.8)

Comorbidities

 Hypertension, n (%)

35 (59.3)

36 (63.2)

 Dyslipidemia, n (%)

25 (42.4)

25 (43.9)

 Chronic kidney disease, n (%)

3 (5.1)

3 (5.3)

 Stroke, n (%)

2 (3.4)

4 (7.0)

 Coronary disease or Heart failure, n (%)

5 (8.5)

4 (7.0)

ESS, median (IQR)

10.2 (5.1)

9.9 (5.4)

mMallampati

 Grade 1, n (%)

2 (3.4)

1 (1.8)

 Grade 2, n (%)

5 (8.5)

10 (17.5)

 Grade 3, n (%)

19 (32.2)

14 (24.6)

 Grade 4, n (%)

33 (55.9)

32 (56.1)

Nasal turbinate

 Normal mucosa, n (%)

56 (94.9)

54 (94.7)

 Pale congestion, n (%)

3 (5.1)

3 (5.3)

AHI, median (IQR)

66.5 (35.1)

63.2 (33.0)

Severity OSA

 Mild, n (%)

1 (1.7)

0 (0.0)

 Moderate, n (%)

10 (16.9)

12 (21.1)

 Severe, n (%)

48 (81.4)

45 (78.9)

 Optimal pressure, mean (SD)

12.2 (4.0)

12.9 (3.2)

Mask type

 Nasal, n (%)

59 (100)

57 (100)

  1. Data shown as mean (SD)or median (interquartile range) or n (%).
  2. BMI = Body Mass Index, AHI = Apnea-Hypopnea index, OSA = Obstructive sleep apnea, ESS = Epworth Sleepiness Scale.