Fig. 5 | Scientific Reports

Fig. 5

From: Complete omission of exon 21 from Slc12a2 transcripts in mice results in hearing loss

Fig. 5

Changes of gene expression in the whole cochleae of Slc12a2Em2/Em2 mice. (A) Heatmap of genes differentially expressed in the whole cochleae of Slc12a2Em2/Em2 and Slc12a2+/+ mice. Red and green indicate higher or lower expression levels in the Slc12a2Em2/Em2 cochlea. (B) Volcano plot of the differentially expressed genes. Genes subjected to qRT-PCR (Supplemental Fig. 7) are indicated. Red and blue dots indicate genes with higher- or lower-expression in Slc12a2Em2/Em2 cochleae. (C-E) Levels of expression of Cldn9 in the developing Slc12a2Em2 cochleae. N = 4.

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