Table 1 Blood gas, lactate, glucose, and hemoglobin before, at the end of insult, and at 1, 3, 6 h after insult in the HI and HI-H2 groups. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 versus HI, #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 versus baseline by two-way ANOVA, post hoc Tukey analysis.

From: Association between hydrogen gas inhalation and cardiac output in an asphyxiated piglet model

 

HI group (n = 10)

HI-H2 group (n = 7)

pH

Baseline

7.46 (0.0)

7.48 (0.0)

0 h

6.93 (0.1) ####

6.97 (0.1) ####

1 h

7.36 (0.1) ##

7.36 (0.1) ##

3 h

7.53 (0.0)

7.52 (0.1)

6 h

7.53 (0.0)

7.49 (0.0)

PaCO2 (mmHg)

Baseline

44.4 (3.1)

42.9 (4.4)

0 h

43.9 (10.9)

43.7 (15.1)

1 h

41.0 (4.02)

42.6 (8.7)

3 h

39.9 (2.98)

40.8 (4.8)

6 h

40.4 (3.48)

42.8 (3.7)

PaO2 (mmHg)

Baseline

92.6 (16.8)

91.0 (17.0)

0 h

20.0 (16.7) ####

11.6 (0.9) ####

1 h

92.4 (23.0)

100.2 (25.7)

3 h

86.6 (21.6)

93.2 (21.6)

6 h

94.8 (22.5)

110.8 (17.9)

BE (mmol/L)

Baseline

8.1 (2.3)

8.0 (2.9)

0 h

-19.2 (10.8) ####

-21.8 (2.9) ####

1 h

-0.7 (6.2) ####

-1.8 (1.6) ###

3 h

9.8 (2.6)

10.1 (2.4)

6 h

10.4 (2.7)

9.5 (1.3)

Lactate (mg/dL)

Baseline

15.6 (5.4)

18.1 (7.4)

0 h

196.0 (23.5) ####

171.1 (42.2) ***####

1 h

102.4 (18.2) ####

101.1 (14.6) ####

3 h

33.3 (16.5)

34.1 (11.0)

6 h

23.1 (11.7)

31.4 (9.4)

Glucose (mg/dL)

Baseline

117.1 (38.7)

114.4 (35.2)

0 h

173.5 (75.4) #

157.7 (48.9) #

1 h

182.7 (52.7)

203.4 (35.5)

3 h

154.2 (60.2)

152.6 (37.3)

6 h

131.5 (36.7)

153.3(30.4)

Hemoglobin (g/dL)

Baseline

10.0 (1.1)

11.2 (1.8)

0 h

10.4 (1.0)

12.1 (2.0)#

1 h

9.9 (1.1)

11.5 (1.8)

3 h

10.3 (0.9)

12.1 (1.7)*#

6 h

10.3 (0.8)

12.1 (1.5)*#