Table 1 Distribution of DAC encoding species in bacterial and archaeal phyla present in the human gut microbiome. For each phylum the number of DAC encoding species (DAC+) is divided by DAC class.

From: Altered abundance in cancer patients gut of diadenylate cyclase-encoding bacteria

Phylum

DAC families

CdaA

CdaA + CdaS

CdaS

DacZ

DisA

DisA + CdaA

DisA + CdaA + CdaS

N° of species DAC+ (% of total species)

Archaea; Halobacteriota

0

0

0

2

1

0

0

3 (100)

Archaea; Methanobacteriota

0

0

0

0

0

0

0

0 (0)

Archaea; Thermoplasmatota

0

0

0

0

0

0

0

0 (0)

Bacteria; Actinobacteriota

0

0

0

0

653

0

0

653 (77.3)

Bacteria; Bacillota

400

3

2

0

43

37

17

502 (94.9)

Bacteria; Bacillota_A

1549

0

0

0

55

176

0

1780 (93.4)

Bacteria; Bacillota_B

2

0

0

0

2

9

0

13 (92.9)

Bacteria; Bacillota_C

137

0

0

0

3

1

0

141 (91.6)

Bacteria; Bacillota_G

0

0

0

0

0

1

0

1 (100)

Bacteria; Bacteroidota

562

0

0

0

8

14

0

584 (94.3)

Bacteria; Bdellovibrionota

0

0

0

0

1

0

0

1 (100)

Bacteria; Campylobacterota

0

0

0

0

0

0

0

0 (0)

Bacteria; Cyanobacteria

60

0

0

0

0

0

0

60 (96.8)

Bacteria; Desulfobacterota

31

0

0

0

0

0

0

31 (93.9)

Bacteria; Elusimicrobiota

0

0

0

0

0

0

0

0 (0)

Bacteria; Eremiobacterota

2

0

0

0

0

0

0

2 (50)

Bacteria; Fibrobacterota

1

0

0

0

0

0

0

1 (100)

Bacteria; Fusobacteriota

0

0

0

0

35

0

0

35 (100)

Bacteria; Myxococcota

1

0

0

0

0

0

0

1 (100)

Bacteria; Patescibacteria

0

0

0

0

0

0

0

0 (0)

Bacteria; Proteobacteria

6

0

0

0

0

0

0

6 (1.7)

Bacteria; Spirochaetota

19

0

0

0

0

0

0

19 (95)

Bacteria; Synergistota

8

0

0

0

0

0

0

8 (100)

Bacteria; Verrucomicrobiota

39

0

0

19

2

0

0

60 (90.9)