Fig. 5

Network analysis to identify biological processes involved in acquired mechanisms of resistance to anti-PD1 inhibitors. (A). Network built using the proteins identified in the analysis of extracellular vesicles in post-treatment samples. Each color represents a functional node to which an overrepresented biological function has been asigned. (B). Differential functional node activities according to progression to anti-PD1 inhibitors in post-treatment samples.