Table 5 Combinations with the most diagnostic Value.

From: Identification of diagnostic and prognostic biomarkers in lung adenocarcinoma through integrated bioinformatics analysis and real time PCR validation

 

AUC

SE

SP

CutOff

ACC

TN

TP

FN

FP

NPV

PPV

CYP2C9.1559

0.504

0.240

0.949

0.910

0.312

56

124

393

3

0.125

0.976

Combination 1

0.964

0.876

0.966

0.902

0.885

57

453

64

2

0.471

0.996

Combination 8

0.629

0.458

0.881

0.901

0.502

52

237

280

7

0.157

0.971

Combination 9

0.538

0.242

0.966

0.918

0.316

57

125

392

2

0.127

0.984

Combination 10

0.750

0.547

0.966

0.921

0.590

57

283

234

2

0.196

0.993

Combination 11

0.761

0.557

0.881

0.922

0.590

52

288

229

7

0.185

0.976

Combination 12

0.574

0.447

0.763

0.894

0.479

45

231

286

14

0.136

0.943

Combination 13

0.950

0.919

0.898

0.848

0.917

53

475

42

6

0.558

0.988

Combination 29

0.970

0.917

0.949

0.864

0.920

56

474

43

3

0.566

0.994

Combination 30

0.965

0.892

0.966

0.882

0.899

57

461

56

2

0.504

0.996

Combination 31

0.968

0.925

0.932

0.835

0.925

55

478

39

4

0.585

0.992

Combination 32

0.973

0.948

0.932

0.796

0.946

55

490

27

4

0.671

0.992

Combination 33

0.971

0.928

0.932

0.842

0.929

55

480

37

4

0.598

0.992

Combination 34

0.987

0.963

0.949

0.759

0.962

56

498

19

3

0.747

0.994

Combination 50

0.663

0.513

0.831

0.901

0.545

49

265

252

10

0.163

0.964

Combination 51

0.807

0.609

0.915

0.918

0.641

54

315

202

5

0.211

0.984

Combination 52

0.815

0.602

0.949

0.925

0.637

56

311

206

3

0.214

0.990

Combination 53

0.662

0.387

0.966

0.931

0.446

57

200

317

2

0.152

0.990

Combination 54

0.955

0.890

0.915

0.895

0.892

54

460

57

5

0.486

0.989

Combination 55

0.752

0.540

0.949

0.924

0.582

56

279

238

3

0.190

0.989

Combination 56

0.769

0.621

0.847

0.913

0.644

50

321

196

9

0.203

0.973

Combination 57

0.609

0.515

0.780

0.894

0.542

46

266

251

13

0.155

0.953

Combination 58

0.951

0.865

0.949

0.910

0.873

56

447

70

3

0.444

0.993

Combination 59

0.842

0.675

0.932

0.914

0.701

55

349

168

4

0.247

0.989

Combination 60

0.766

0.605

0.915

0.909

0.637

54

313

204

5

0.209

0.984

Combination 61

0.969

0.923

0.915

0.864

0.922

54

477

40

5

0.574

0.990

Combination 62

0.783

0.644

0.814

0.909

0.661

48

333

184

11

0.207

0.968

Combination 63

0.959

0.880

0.949

0.898

0.887

56

455

62

3

0.475

0.993

Combination 64

0.954

0.897

0.932

0.888

0.901

55

464

53

4

0.509

0.991

Combination 120

0.809

0.600

0.915

0.924

0.632

54

310

207

5

0.207

0.984

Combination 121

0.822

0.687

0.847

0.901

0.703

50

355

162

9

0.236

0.975

Combination 122

0.690

0.464

0.898

0.919

0.509

53

240

277

6

0.161

0.976

Combination 123

0.956

0.863

0.949

0.922

0.872

56

446

71

3

0.441

0.993

Combination 124

0.874

0.737

0.881

0.898

0.752

52

381

136

7

0.277

0.982

Combination 125

0.813

0.567

0.949

0.937

0.606

56

293

224

3

0.200

0.990

Combination 126

0.972

0.952

0.881

0.737

0.944

52

492

25

7

0.675

0.986

Combination 127

0.829

0.578

0.983

0.936

0.620

58

299

218

1

0.210

0.997

Combination 128

0.964

0.896

0.949

0.893

0.901

56

463

54

3

0.509

0.994

Combination 129

0.957

0.901

0.915

0.882

0.903

54

466

51

5

0.514

0.989

Combination 130

0.843

0.725

0.898

0.899

0.743

53

375

142

6

0.272

0.984

Combination 131

0.767

0.613

0.898

0.905

0.642

53

317

200

6

0.209

0.981

Combination 132

0.969

0.956

0.881

0.762

0.948

52

494

23

7

0.693

0.986

Combination 133

0.790

0.571

0.881

0.925

0.602

52

295

222

7

0.190

0.977

Combination 134

0.959

0.890

0.949

0.890

0.896

56

460

57

3

0.496

0.994

Combination 135

0.954

0.909

0.898

0.870

0.908

53

470

47

6

0.530

0.987

Combination 136

0.850

0.716

0.898

0.901

0.734

53

370

147

6

0.265

0.984

Combination 137

0.974

0.919

0.932

0.878

0.920

55

475

42

4

0.567

0.992

Combination 138

0.969

0.956

0.881

0.745

0.948

52

494

23

7

0.693

0.986

Combination 139

0.961

0.894

0.932

0.884

0.898

55

462

55

4

0.500

0.991

Combination 155

0.972

0.884

0.983

0.913

0.894

58

457

60

1

0.492

0.998

Combination 156

0.979

0.915

0.966

0.881

0.920

57

473

44

2

0.564

0.996

Combination 157

0.975

0.936

0.932

0.804

0.936

55

484

33

4

0.625

0.992

Combination 158

0.988

0.959

0.949

0.789

0.958

56

496

21

3

0.727

0.994