Table 5 Combinations with the most diagnostic Value.
AUC | SE | SP | CutOff | ACC | TN | TP | FN | FP | NPV | PPV | |
|---|---|---|---|---|---|---|---|---|---|---|---|
CYP2C9.1559 | 0.504 | 0.240 | 0.949 | 0.910 | 0.312 | 56 | 124 | 393 | 3 | 0.125 | 0.976 |
Combination 1 | 0.964 | 0.876 | 0.966 | 0.902 | 0.885 | 57 | 453 | 64 | 2 | 0.471 | 0.996 |
Combination 8 | 0.629 | 0.458 | 0.881 | 0.901 | 0.502 | 52 | 237 | 280 | 7 | 0.157 | 0.971 |
Combination 9 | 0.538 | 0.242 | 0.966 | 0.918 | 0.316 | 57 | 125 | 392 | 2 | 0.127 | 0.984 |
Combination 10 | 0.750 | 0.547 | 0.966 | 0.921 | 0.590 | 57 | 283 | 234 | 2 | 0.196 | 0.993 |
Combination 11 | 0.761 | 0.557 | 0.881 | 0.922 | 0.590 | 52 | 288 | 229 | 7 | 0.185 | 0.976 |
Combination 12 | 0.574 | 0.447 | 0.763 | 0.894 | 0.479 | 45 | 231 | 286 | 14 | 0.136 | 0.943 |
Combination 13 | 0.950 | 0.919 | 0.898 | 0.848 | 0.917 | 53 | 475 | 42 | 6 | 0.558 | 0.988 |
Combination 29 | 0.970 | 0.917 | 0.949 | 0.864 | 0.920 | 56 | 474 | 43 | 3 | 0.566 | 0.994 |
Combination 30 | 0.965 | 0.892 | 0.966 | 0.882 | 0.899 | 57 | 461 | 56 | 2 | 0.504 | 0.996 |
Combination 31 | 0.968 | 0.925 | 0.932 | 0.835 | 0.925 | 55 | 478 | 39 | 4 | 0.585 | 0.992 |
Combination 32 | 0.973 | 0.948 | 0.932 | 0.796 | 0.946 | 55 | 490 | 27 | 4 | 0.671 | 0.992 |
Combination 33 | 0.971 | 0.928 | 0.932 | 0.842 | 0.929 | 55 | 480 | 37 | 4 | 0.598 | 0.992 |
Combination 34 | 0.987 | 0.963 | 0.949 | 0.759 | 0.962 | 56 | 498 | 19 | 3 | 0.747 | 0.994 |
Combination 50 | 0.663 | 0.513 | 0.831 | 0.901 | 0.545 | 49 | 265 | 252 | 10 | 0.163 | 0.964 |
Combination 51 | 0.807 | 0.609 | 0.915 | 0.918 | 0.641 | 54 | 315 | 202 | 5 | 0.211 | 0.984 |
Combination 52 | 0.815 | 0.602 | 0.949 | 0.925 | 0.637 | 56 | 311 | 206 | 3 | 0.214 | 0.990 |
Combination 53 | 0.662 | 0.387 | 0.966 | 0.931 | 0.446 | 57 | 200 | 317 | 2 | 0.152 | 0.990 |
Combination 54 | 0.955 | 0.890 | 0.915 | 0.895 | 0.892 | 54 | 460 | 57 | 5 | 0.486 | 0.989 |
Combination 55 | 0.752 | 0.540 | 0.949 | 0.924 | 0.582 | 56 | 279 | 238 | 3 | 0.190 | 0.989 |
Combination 56 | 0.769 | 0.621 | 0.847 | 0.913 | 0.644 | 50 | 321 | 196 | 9 | 0.203 | 0.973 |
Combination 57 | 0.609 | 0.515 | 0.780 | 0.894 | 0.542 | 46 | 266 | 251 | 13 | 0.155 | 0.953 |
Combination 58 | 0.951 | 0.865 | 0.949 | 0.910 | 0.873 | 56 | 447 | 70 | 3 | 0.444 | 0.993 |
Combination 59 | 0.842 | 0.675 | 0.932 | 0.914 | 0.701 | 55 | 349 | 168 | 4 | 0.247 | 0.989 |
Combination 60 | 0.766 | 0.605 | 0.915 | 0.909 | 0.637 | 54 | 313 | 204 | 5 | 0.209 | 0.984 |
Combination 61 | 0.969 | 0.923 | 0.915 | 0.864 | 0.922 | 54 | 477 | 40 | 5 | 0.574 | 0.990 |
Combination 62 | 0.783 | 0.644 | 0.814 | 0.909 | 0.661 | 48 | 333 | 184 | 11 | 0.207 | 0.968 |
Combination 63 | 0.959 | 0.880 | 0.949 | 0.898 | 0.887 | 56 | 455 | 62 | 3 | 0.475 | 0.993 |
Combination 64 | 0.954 | 0.897 | 0.932 | 0.888 | 0.901 | 55 | 464 | 53 | 4 | 0.509 | 0.991 |
Combination 120 | 0.809 | 0.600 | 0.915 | 0.924 | 0.632 | 54 | 310 | 207 | 5 | 0.207 | 0.984 |
Combination 121 | 0.822 | 0.687 | 0.847 | 0.901 | 0.703 | 50 | 355 | 162 | 9 | 0.236 | 0.975 |
Combination 122 | 0.690 | 0.464 | 0.898 | 0.919 | 0.509 | 53 | 240 | 277 | 6 | 0.161 | 0.976 |
Combination 123 | 0.956 | 0.863 | 0.949 | 0.922 | 0.872 | 56 | 446 | 71 | 3 | 0.441 | 0.993 |
Combination 124 | 0.874 | 0.737 | 0.881 | 0.898 | 0.752 | 52 | 381 | 136 | 7 | 0.277 | 0.982 |
Combination 125 | 0.813 | 0.567 | 0.949 | 0.937 | 0.606 | 56 | 293 | 224 | 3 | 0.200 | 0.990 |
Combination 126 | 0.972 | 0.952 | 0.881 | 0.737 | 0.944 | 52 | 492 | 25 | 7 | 0.675 | 0.986 |
Combination 127 | 0.829 | 0.578 | 0.983 | 0.936 | 0.620 | 58 | 299 | 218 | 1 | 0.210 | 0.997 |
Combination 128 | 0.964 | 0.896 | 0.949 | 0.893 | 0.901 | 56 | 463 | 54 | 3 | 0.509 | 0.994 |
Combination 129 | 0.957 | 0.901 | 0.915 | 0.882 | 0.903 | 54 | 466 | 51 | 5 | 0.514 | 0.989 |
Combination 130 | 0.843 | 0.725 | 0.898 | 0.899 | 0.743 | 53 | 375 | 142 | 6 | 0.272 | 0.984 |
Combination 131 | 0.767 | 0.613 | 0.898 | 0.905 | 0.642 | 53 | 317 | 200 | 6 | 0.209 | 0.981 |
Combination 132 | 0.969 | 0.956 | 0.881 | 0.762 | 0.948 | 52 | 494 | 23 | 7 | 0.693 | 0.986 |
Combination 133 | 0.790 | 0.571 | 0.881 | 0.925 | 0.602 | 52 | 295 | 222 | 7 | 0.190 | 0.977 |
Combination 134 | 0.959 | 0.890 | 0.949 | 0.890 | 0.896 | 56 | 460 | 57 | 3 | 0.496 | 0.994 |
Combination 135 | 0.954 | 0.909 | 0.898 | 0.870 | 0.908 | 53 | 470 | 47 | 6 | 0.530 | 0.987 |
Combination 136 | 0.850 | 0.716 | 0.898 | 0.901 | 0.734 | 53 | 370 | 147 | 6 | 0.265 | 0.984 |
Combination 137 | 0.974 | 0.919 | 0.932 | 0.878 | 0.920 | 55 | 475 | 42 | 4 | 0.567 | 0.992 |
Combination 138 | 0.969 | 0.956 | 0.881 | 0.745 | 0.948 | 52 | 494 | 23 | 7 | 0.693 | 0.986 |
Combination 139 | 0.961 | 0.894 | 0.932 | 0.884 | 0.898 | 55 | 462 | 55 | 4 | 0.500 | 0.991 |
Combination 155 | 0.972 | 0.884 | 0.983 | 0.913 | 0.894 | 58 | 457 | 60 | 1 | 0.492 | 0.998 |
Combination 156 | 0.979 | 0.915 | 0.966 | 0.881 | 0.920 | 57 | 473 | 44 | 2 | 0.564 | 0.996 |
Combination 157 | 0.975 | 0.936 | 0.932 | 0.804 | 0.936 | 55 | 484 | 33 | 4 | 0.625 | 0.992 |
Combination 158 | 0.988 | 0.959 | 0.949 | 0.789 | 0.958 | 56 | 496 | 21 | 3 | 0.727 | 0.994 |