Fig. 6

Natural killer (NK) and T cell subsets in the pediatric CF and control lungs. (A) UMAP visualization of the five identified NK and T cell subsets in the BALF specimens collected from pediatric patients with CF (n = 2) and pediatric controls (CO) (n = 3) divided by disease state and colored by subset. (B) Dot plot visualization of the top differentially expressed genes in each NK and T cell subset by expression level and frequency. (C) Stacked column chart visualization of the distributions of the NK and T cell subsets by disease state and subsequently by pediatric patient. Treg: Regulatory CD4 + T cells.