Table 2 Threshold effect analysis of the relationship between each 100 µmol/L increase in UA and PE.

From: Elevated serum uric acid before 20 weeks of gestation increases the risk of preeclampsia

Models

Risk of PE Adjusted OR (95%CI)

P value

Model I

One line slope

2.20 (2.04, 2.37)

<0.0001

Model II

Turning point (K)

240 µmol/L

 

UA < 240 slope 1

1.81 (1.55, 2.11)

<0.0001

UA ≥ 240 slope 2

2.54 (2.24, 2.88)

<0.0001

Slope 2–Slope 1

1.41 (1.11, 1.78)

0.0053

Predicted at 240

−2.81 (−2.88, −2.74)

 

P for Log-likelihood ratio

 

0.006

  1. Model I, linear analysis; Model II, non-linear analysis.
  2. Adjust for age, BMI, systolic pressure, diastolic pressure, aspirin, depressor, family history of hypertension, tobacco, alcohol, IVF, parity, alanine transaminase, total cholesterol, triglycerides, fasting blood glucose, test week, adverse pregnancy history.
  3. UA, uric acid; PE, preeclampsia; CI, confidence interval.
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