Fig. 5

Molecular dynamics simulation analysis of protein stability over 50 ns. A Root Mean Square Deviation (RMSD) of the apo protein and its complexes with Yibeinoside A, Vomicine, and Lorlatinib. B Root Mean Square Fluctuation (RMSF) of the apo protein and its complexes with Yibeinoside A, Vomicine, and Lorlatinib.