Table 3 Thrombin generation parameters.

From: Predicting dialyzer fiber blocking is hard due to high intrapatient variability and limited utility of thrombin generation markers

 

ETPp

nM. min

Thrombin peak

nM

Lag time

min

Time to peak

min

Velocity index

nM/min

 

At the dialysis start

 Full antico

1702 ± 438

331 ± 62

6.0 ± 1.2

15.9 ± 3.6

38 ± 14

 1/4 antico

1520 ± 342

310 ± 53

5.4 ± 1.0

14.7 ± 2.2

36 ± 10

 P (full vs. 1/4)

0.055

0.176

0.370

0.131

0.658

 

At the dialysis end

 Full antico

1738 ± 517

345 ± 75

10.0 ± 2.8

19.9 ± 3.3

40 ± 16

 1/4 antico

1446 ± 413

365 ± 113

5.9 ± 1.4

13.6 ± 2.1

54 ± 29

 P (full vs. 1/4)

0.025

0.318

< 0.001

< 0.001

0.011

 P (start vs. end)

0.769

0.008

< 0.001

0.035

0.003

  1. ETPp: endogenous thrombin potential until the thrombin peak.
  2. Significant values are in bold.
Back to article page