Fig. 8 | Scientific Reports

Fig. 8

From: CKAAKN peptide-conjugated long-circulating nanoliposomes for the targeted delivery of oridonin to pancreatic cancers

Fig. 8

In vivo biodistribution of DiR-labeled liposomes in an orthotopic pancreatic cancer model. (A) Whole-body fluorescence imaging at different time points after intravenous injection. (B) Ex vivo tissue distribution at 48 h post-injection of ORI@Lipo. (C) Quantitative tissue accumulation (%ID/g) of ORI@Lipo. (D) Representative images at 48 h after ORI@CPD-Lipo injection: (a) whole-mouse photograph, (b) corresponding fluorescence image, (c) tumor and normal pancreatic tissue, (d) fluorescence of tumor and pancreas. (E) Ex vivo tissue distribution at 48 h post-injection of ORI@CPD-Lipo. (F) Quantitative tissue accumulation (%ID/g) of ORI@CPD-Lipo. Fluorescence intensity reflects liposome concentration; %ID/g denotes percentage of injected dose per gram of tissue.

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