Fig. 1 | Scientific Reports

Fig. 1

From: Integrated analysis of global regulators and efflux genes associated with antimicrobial resistance reversal in multidrug resistant Klebsiella pneumoniae

Fig. 1

Relative expression levels of global regulators (marA, soxS, rob) and efflux pump genes (acrA, acrB, tolC) in multidrug-resistant (MDR) and susceptible Klebsiella pneumoniae isolates. Bars represent mean fold-change values calculated using the 2⁻ΔΔCt method relative to the susceptible control (baseline = 1), normalized to 16S rRNA. Error bars indicate standard deviation (SD). Each dot represents an individual clinical isolate (susceptible, n = 10; MDR, n = 30), illustrating data distribution and inter-isolate variability. Note: Statistical significance was assessed using unpaired two-sample t-tests on ΔCt values (MDR vs. susceptible group) with Bonferroni correction (adjusted α = 0.0083).

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