Table 2 Antibiotic Resistance Profiles of MDR K. pneumoniae Isolates (n = 30).
Antibiotic Class | Agent(s) | Resistance in MDR Isolates | MIC (MDR Isolates) | MIC (Control Isolates) | Notes |
|---|---|---|---|---|---|
Fluoroquinolones | Ciprofloxacin | 100% (30/30) | 8 – > 64 µg/mL | ≤ 0.5 µg/mL | No/ ≤ 15 mm zone in disk diffusion |
Aminoglycosides | Gentamicin | 100% (30/30) | 8 – 32 µg/mL | ≤ 2 µg/mL | Markedly elevated MICs |
3rd Gen Cephalosporins | CTX / CAZ | 90% (27/30) | Resistant (not specified) | ≤ 1 µg/mL | Confirmed ESBL phenotype via synergy tests |
Carbapenems | Imipenem / Meropenem | 20% (6/30) | ≥ 16 µg/mL | ≤ 1 µg/mL | Suggests the presence of carbapenemases |
Folate Inhibitors & Tetracyclines | TMP-SMX | 100% (30/30) | Not specified | ≤ 0.5 µg/mL | Universally resistant |
Tetracycline | 100% (30/30) | Not specified | ≤ 2 µg/mL | Universally resistant |