Table 4 Pearson correlation between gene expression and ciprofloxacin resistance in MDR K. pneumoniae (n = 30 biological isolates). Correlation coefficients were calculated using per-isolate fold-change values derived from qRT-PCR assays performed in technical triplicates.

From: Integrated analysis of global regulators and efflux genes associated with antimicrobial resistance reversal in multidrug resistant Klebsiella pneumoniae

Comparison

Pearson r

p-value

Significance

marA expression vs. soxS expression

0.50

0.005

Significant (**)

marA expression vs. acrB Expression

0.75

 < 0.001

Highly Significant (**)

soxS Expression vs. acrB Expression

0.83

 < 0.001

Highly Significant (**)

rob expression vs. acrB Expression

0.07

0.70 (ns)

Not Significant

acrB Expression vs. Ciprofloxacin MIC

0.56

0.001

Significant (**)

marA expression vs. Gentamicin MIC

0.09

0.65 (ns)

Not Significant

  1. Indicates statistically significant correlation at p < 0.0083 (Bonferroni-corrected). ns indicates non-significant correlation (p ≥ 0.0083).
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