Fig. 6
From: Targeting the Akt–EphA2 axis and cell–cell adhesion enhances anoikis sensitivity in cancer cells
Illustrated Working Model. Schematic model depicting the distinct signaling pathways activated in breast cancer cells (MDA-EV) and Tpm2.1-expressing cells (MDA-Tpm2.1), following their separation into non-apoptotic (TpmNoAp) and apoptotic (TpmApop) subpopulations after 5 h and 4 days in suspension. The model highlights subpopulation-specific pathway adaptations and the associated cellular fates under anchorage-independent conditions. Created in https://BioRender.com.
