Abstract
In this single-center retrospective study, we compared visual performance and optical quality between a new refractive extended depth-of-focus intraocular lens (EDoF IOL, Model ZEN00V, n = 44), with a slightly myopic target, and an enhanced monofocal IOL (Model ICB00, n = 44), with the target refraction closest to emmetropia on the myopic side. The IOL power for the EDoF IOL was selected to achieve postoperative refraction of -0.50 to -1.00 D. Monocular distance visual acuity (VA) and iTrace aberrometry were assessed. Bilateral cases were analyzed to evaluate intermediate and near VA, and photic phenomena. Preoperative target diopter and postoperative spherical equivalent were more myopic in the EDoF IOL group than in the monofocal IOL group (all p < 0.001). Uncorrected and corrected distance VA were comparable between the two groups (all p > 0.05). Higher order aberrations were comparable between the two groups (all p > 0.05) except for spherical aberrations, which were lower in the monofocal group (p = 0.002). Subgroup analysis revealed superior near VA (p = 0.02) and an extended range of defocus in the EDoF IOL group with comparable photic phenomena. Implantation of the new refractive EDoF IOL, the TECNIS PureSee™, with myopic target diopter may be a viable option for improving intermediate and near visual performance while preserving distance vision and visual quality.
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Data availability
The datasets used during the current study are available from the corresponding author on reasonable request. All data generated or analyzed during this study are included in this published article.
Abbreviations
- ACD:
-
Anterior chamber depth
- AL:
-
Axial length
- CCT:
-
Central corneal thickness
- CDVA:
-
Corrected distance visual acuity
- D:
-
Diopter
- ETDRS:
-
Early treatment diabetic retinopathy study
- EDoF IOL:
-
Extended depth-of-focus intraocular lens
- HOA:
-
High-order aberration
- IOL:
-
Intraocular lens
- logMAR:
-
Logarithm of the minimum angle of resolution
- RMS:
-
Root mean square
- UDVA:
-
Uncorrected distance
- VA:
-
Visual acuity
- WTW:
-
White-to-white
- SE:
-
Spherical equivalent
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Acknowledgements
This work was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health &Welfare, Republic of Korea (Grant number: RS-2023-00302193).
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Conceptualization with study design and hypothesis generation, H.L., D.Y.K., H.W.P., J.O., I.H.J., K.Y.S., A.E. and T.I.K.; Data collection and screening, H.L., D.Y.K., H.W.P., J.O. and T..K.; investigation including literature research and evidence synthesis, H.L., D.Y.K., A.E., and T.I.K., formal analysis, H.L., D.Y.K., and T.I.K.; writing—original draft preparation, H.L., D.Y.K., and T.I.K.; writing—review and editing with contributions from all co-authors. All authors have reviewed and agreed to the final version of the manuscript.
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Lee, H., Kim, D.Y., Oh, J. et al. Higher-order aberrations and visual outcomes of a new refractive extended depth-of-focus intraocular lens with a target of slight myopia. Sci Rep (2026). https://doi.org/10.1038/s41598-026-37674-w
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DOI: https://doi.org/10.1038/s41598-026-37674-w
