Fig. 2 | Scientific Reports

Fig. 2

From: Multi-omics analysis reveals sevoflurane exacerbates cognitive impairment in diabetic mice by disrupting lipid metabolism

Fig. 2The alternative text for this image may have been generated using AI.

Effects of anesthetics on hippocampal neuronal pathology in T1DM mice.(A-C) Representative immunofluorescence images and semi-quantitative analysis of (A) NeuN-, (B) Aβ1−42-, and (C) SYN-positive area in the hippocampal region (n = 6). Scale bars, 50 µm (NeuN, SYN) or 100 µm (Aβ1−42). *P < 0.05, **P < 0.01, ***P < 0.001 vs. CON group; @@P < 0.01, @@@P < 0.001 vs. DM + PRO group; &&&P < 0.001 vs. DM + SEV group. Data are mean ± SEM. P values were determined by two-way ANOVA followed by Bonferroni’ s multiple comparisons

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